Ovarian failure following abdominal irradiation in childhood.
Shalet, Stephen M Beardwell, Colin G Jones, P H Pearson, D Orrell, D
Shalet, Stephen M
Beardwell, Colin G
Jones, P H
Pearson, D
Orrell, D
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Abstract
Ovarian function was studied in 18 female patients treated for abdominal tumours during childhood. All received abdominal radiotherapy as part of their treatment and were studied between 1 and 26 years after irradiation. The serum gonadotrophins and oestradiol levels were consistent with ovarian failure in each case but there was a disproportionate elevation in serum follicle stimulating hormone (FSH) when compared to serum luteinizing hormone (LH) in 16. In 2 patients, the radiotherapeutic field extended downwards only as far as the sacral promontory. However, these 2 girls show similar evidence of ovarian failure to that in the other 16.
Affiliation
Description
Date
1976-06
Publisher
Collections
Keywords
Abdominal Cancer
Type
Article
Citation
Ovarian failure following abdominal irradiation in childhood. 1976, 33 (6):655-8 Br J Cancer