The structural basis for C-banding. A scanning electron microscopy study.
Jack, Elspeth M Harrison, Christine J Allen, Terence D Harris, R
Jack, Elspeth M
Harrison, Christine J
Allen, Terence D
Harris, R
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Abstract
The same C-banded human polymorphic chromosomes were observed in the light microscope (LM) and then in the scanning electron microscope (SEM) to investigate the structural changes produced by the C-banding technique. C-banded regions, which stained positively in LM, were highly condensed with tightly packed chromatin fibres, resembling non-banded chromosomes. In striking contrast, adjacent non-C-banded regions were represented by loosely arranged fibres, resembling G-banded chromosomes. The significance of these observations in relation to current theories on the effects of C-banding on chromosome structure is discussed.
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Date
1985
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Collections
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Article
Citation
The structural basis for C-banding. A scanning electron microscopy study. 1985, 91 (5):363-8 Chromosoma