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Local control following stereotactic body radiation therapy for liver oligometastases: lessons from a quarter century
Mheid, S Allen, S Ng, SSW Hall, WA Sanford, NN Aguilera, TA Elamir, AM Bahij, R Intven, MPW Radhakrishna, Ganesh
Mheid, S
Allen, S
Ng, SSW
Hall, WA
Sanford, NN
Aguilera, TA
Elamir, AM
Bahij, R
Intven, MPW
Radhakrishna, Ganesh
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Abstract
The utilization of stereotactic body radiation therapy for the treatment of liver metastasis has been widely studied and has demonstrated favorable local control outcomes. However, several predictive factors play a crucial role in the efficacy of stereotactic body radiation therapy, such as the number and size (volume) of metastatic liver lesions, the primary tumor site (histology), molecular biomarkers (e.g., KRAS and TP53 mutation), the use of systemic therapy prior to SBRT, the radiation dose, and the use of advanced technology and organ motion management during SBRT. These prognostic factors need to be considered when clinical trials are designed to evaluate the efficacy of SBRT for liver metastases.
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2023
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Mheid S, Allen S, Ng SSW, Hall WA, Sanford NN, Aguilera TA, et al. Local Control Following Stereotactic Body Radiation Therapy for Liver Oligometastases: Lessons from a Quarter Century. CURRENT ONCOLOGY. 2023 OCT;30(10):9230-43. PubMed PMID: WOS:001094095600001. English.