Loading...
Three cytotoxic drugs combined with pelvic radiation and as maintenance chemotherapy for patients with squamous cell carcinoma of the anus (SCCA): long-term follow-up of a phase II pilot study using 5-fluorouracil, mitomycin C and cisplatin.
Sebag-Montefiore, D Meadows, H Cunningham, D Plowman, P Hurman, D Davidson, N Grieve, R Levine, Edward Glynne-Jones, R
Sebag-Montefiore, D
Meadows, H
Cunningham, D
Plowman, P
Hurman, D
Davidson, N
Grieve, R
Levine, Edward
Glynne-Jones, R
Citations
Altmetric:
Abstract
Phase III trials in the 1990s for squamous cell carcinoma of the anus (SCCA) demonstrated 5-fluorouracil (5FU) and mitomycinC (MMC) chemoradiation (CRT) improved outcome compared to radiation (RT) alone, but local recurrence remained significant. This prospective pilot study intensified treatment by integrating 3 cytotoxic drugs into CRT and maintenance chemotherapy.
Description
Date
2012-08
Publisher
Collections
Keywords
Type
Article
Citation
Three cytotoxic drugs combined with pelvic radiation and as maintenance chemotherapy for patients with squamous cell carcinoma of the anus (SCCA): long-term follow-up of a phase II pilot study using 5-fluorouracil, mitomycin C and cisplatin. 2012, 104 (2):155-60 Radiother Oncol