Elastase activity in capillary and aortic endothelial cells.
West, David C Kumar, Shant
West, David C
Kumar, Shant
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Abstract
Tissue cultured bovine capillary and aortic endothelial cells were examined for cellular and secreted proteinase activity. Cell-lysates from both sources showed significant elastase activity but differed in the level of activity and the pH-optimum and inhibition profile. Secretion of elastase was only detected using aortic cells. Tumour angiogenesis factor (TAF), heparin or 12-0-tetradecanoyl-phorbol-acetate (TPA) had no effect on the levels of cell-associated or secreted elastase.
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1986
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Elastase activity in capillary and aortic endothelial cells., 6 (5):1069-72 Anticancer Res