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24-hour cyclophosphamide infusion therapy for malignant mesothelioma of the pleura.
Anderson, Heather Hasleton, Philip S Michie, A B Johnson, Richard J Thatcher, Nick
Anderson, Heather
Hasleton, Philip S
Michie, A B
Johnson, Richard J
Thatcher, Nick
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Abstract
Thirteen patients with malignant mesothelioma of the pleura have been treated with 24-hour cyclophosphamide infusion (2.5 g/m2) therapy. There were no complete responders. Three patients (23%) had a partial response, and a further three patients who did not fulfil the criteria for objective response, had subjective benefit from therapy with increase in performance status. The overall median survival from the onset of therapy was 6 months (range 2-19 months). High dose cyclophosphamide offers no advantage over standard dose therapy.
Description
Date
1988-01
Publisher
Collections
Keywords
Pleural Cancer
Type
Citation
24-hour cyclophosphamide infusion therapy for malignant mesothelioma of the pleura. 1988, 82 (1):64-9 Br J Dis Chest