Patients with a high polygenic risk of breast cancer do not have an increased risk of radiotherapy toxicity.
Dorling, L Barnett, G Michailidou, K Coles, C Burnet, N Yarnold, J Elliott, Rebecca M Dunning, A Pharoah, P West, Catharine M L
Dorling, L
Barnett, G
Michailidou, K
Coles, C
Burnet, N
Yarnold, J
Elliott, Rebecca M
Dunning, A
Pharoah, P
West, Catharine M L
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Abstract
It has been hypothesized that increased predisposition to breast cancer may correlate with radiosensitivity and thus increased risk of toxicity following breast irradiation. This study investigated the relationship between common breast cancer risk variants and radiotherapy toxicity.
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Date
2015-10-28
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Patients with a high polygenic risk of breast cancer do not have an increased risk of radiotherapy toxicity. 2015: Clin Cancer Res