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Duration of adjuvant chemotherapy for stage III colon cancer.
Grothey, A Sobrero, A Shields, A Yoshino, T Paul, J Taieb, J Souglakos, J Shi, Q Kerr, R Labianca, R
Grothey, A
Sobrero, A
Shields, A
Yoshino, T
Paul, J
Taieb, J
Souglakos, J
Shi, Q
Kerr, R
Labianca, R
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Abstract
Since 2004, a regimen of 6 months of treatment with oxaliplatin plus a fluoropyrimidine has been standard adjuvant therapy in patients with stage III colon cancer. However, since oxaliplatin is associated with cumulative neurotoxicity, a shorter duration of therapy could spare toxic effects and health expenditures.
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Date
2018
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160340.pdf
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Article
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Duration of adjuvant chemotherapy for stage III colon cancer. 2018, 378(13): 1177-1188 N Engl J Med