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Primary mutational landscape linked with pre-docetaxel lactate dehydrogenase levels predicts docetaxel response in metastatic castrate-resistant prostate cancer.
Hiew, Kenneth ; Hart, Claire A ; Ali, Adnan ; ; Ramani, Vijay A C ; Sangar, Vijay K ; Lau, Maurice W ; Maddineni, Satish B ; Brown, Michael D ;
Hiew, Kenneth
Hart, Claire A
Ali, Adnan
Ramani, Vijay A C
Sangar, Vijay K
Lau, Maurice W
Maddineni, Satish B
Brown, Michael D
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Abstract
Docetaxel chemotherapy is a standard of care for metastatic castrate-resistant prostate cancer (mCRPC): 40-50% of patients achieve a biochemical response. However, there is a lack of response predictive biomarkers.
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2018-04-23
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Primary mutational landscape linked with pre-docetaxel lactate dehydrogenase levels predicts docetaxel response in metastatic castrate-resistant prostate cancer. 2018, Eur Urol Focus