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Sex and interleukin-6 are prognostic factors for autoimmune toxicity following treatment with anti-CTLA4 blockade.
Valpione, Sara Pasquali, S Campana, L Piccin, L Mocellin, S Pigozzo, J Chiarion-Sileni, V
Valpione, Sara
Pasquali, S
Campana, L
Piccin, L
Mocellin, S
Pigozzo, J
Chiarion-Sileni, V
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Abstract
Ipilimumab is a licensed immunotherapy for metastatic melanoma patients and, in the US, as adjuvant treatment for high risk melanoma radically resected. The use of ipilimumab is associated with a typical but unpredictable pattern of side effects. The purpose of this study was to identify clinical features and blood biomarkers capable of predicting ipilimumab related toxicity.
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2018-04-11
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Sex and interleukin-6 are prognostic factors for autoimmune toxicity following treatment with anti-CTLA4 blockade. 2018, 16(1): 94 J Transl Med