Epithelial stem cells in the mammary gland: casting light into dark corners.
Anderson, Elizabeth Clarke, Robert B
Anderson, Elizabeth
Clarke, Robert B
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Abstract
The epithelial structures of the human breast or the mouse mammary gland are derived from a relatively small number of multipotent, tissue-specific stem cells, of which we are surprisingly ignorant. We do not know how many are required to produce a complete mammary gland, how many times they divide during the process, where they are situated in the gland, or even what they look like. We want to know the answers to these questions, not just to satisfy intellectual curiosity, but also because the answers may shed light on the evolution of breast cancer. Now, studies carried out by Kordon and Smith at the National Cancer Institute have pointed the way toward a new understanding of mammary stem cells and their progeny.
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Description
Date
1999
Publisher
Collections
Keywords
Breast Cancer
Type
Article
Citation
Epithelial stem cells in the mammary gland: casting light into dark corners. 1999, 1 (1):11-3 Breast Cancer Res.