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Choice of a patient-reported outcome measure for patients with anal cancer for use in cancer clinical trials and routine clinical practice: a mixed methods approach.
Gilbert, A Francischetto, E Blazeby, J Holch, P Davidson, Susan E Sebag-Montefiore, D Velikova, G
Gilbert, A
Francischetto, E
Blazeby, J
Holch, P
Davidson, Susan E
Sebag-Montefiore, D
Velikova, G
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Abstract
In the USA, more than 7200 new cases of anal cancer were diagnosed in 2014 with incidence rising. Concurrent chemoradiotherapy improves cancer-related outcomes but has led to an increase in acute and late adverse events. Patient-reported outcomes (PRO) are increasingly included in trials as a surrogate measure for reporting of late adverse events. This study aimed to select the most effective PRO to use in clinical research and practice for anal cancer since no questionnaire specific for anal cancer has been developed.
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2015-02-26
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Choice of a patient-reported outcome measure for patients with anal cancer for use in cancer clinical trials and routine clinical practice: a mixed methods approach. 2015, 385 Suppl 1:S38 Lancet