Residual Ph- cells in chronic myeloid leukemia: detection and usefulness.

2.50
Hdl Handle:
http://hdl.handle.net/10541/99943
Title:
Residual Ph- cells in chronic myeloid leukemia: detection and usefulness.
Authors:
Chang, James; Coutinho, Lucia H; Santos, A M; Brereton, M L; Harrison, Christine J; Testa, Nydia G
Abstract:
Bone marrow cells from patients with chronic myeloid leukemia (CML) in in vitro long-term bone marrow culture (LTBMC) show an impaired survival of Philadelphia (Ph) positive cells and, in a proportion of patients, the emergence of Philadelphia negative hemopoiesis. The standard conditions of in vitro cultures provide optimal purging effect. Selected patients can now have autologous bone marrow transplants (ABMT) with in vitro purged cells.
Affiliation:
Department of Experimental Hematology, Paterson Institute for Cancer Research, Christie Hospital, Manchester, United Kingdom.
Citation:
Residual Ph- cells in chronic myeloid leukemia: detection and usefulness. 1993, 11 Suppl 1:59-61 Stem Cells
Journal:
Stem Cells
Issue Date:
May-1993
URI:
http://hdl.handle.net/10541/99943
DOI:
10.1002/stem.5530110612
PubMed ID:
8318920
Type:
Article
Language:
en
ISSN:
1066-5099
Appears in Collections:
All Christie Publications ; All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorChang, Jamesen
dc.contributor.authorCoutinho, Lucia Hen
dc.contributor.authorSantos, A Men
dc.contributor.authorBrereton, M Len
dc.contributor.authorHarrison, Christine Jen
dc.contributor.authorTesta, Nydia Gen
dc.date.accessioned2010-05-27T15:05:24Z-
dc.date.available2010-05-27T15:05:24Z-
dc.date.issued1993-05-
dc.identifier.citationResidual Ph- cells in chronic myeloid leukemia: detection and usefulness. 1993, 11 Suppl 1:59-61 Stem Cellsen
dc.identifier.issn1066-5099-
dc.identifier.pmid8318920-
dc.identifier.doi10.1002/stem.5530110612-
dc.identifier.urihttp://hdl.handle.net/10541/99943-
dc.description.abstractBone marrow cells from patients with chronic myeloid leukemia (CML) in in vitro long-term bone marrow culture (LTBMC) show an impaired survival of Philadelphia (Ph) positive cells and, in a proportion of patients, the emergence of Philadelphia negative hemopoiesis. The standard conditions of in vitro cultures provide optimal purging effect. Selected patients can now have autologous bone marrow transplants (ABMT) with in vitro purged cells.en
dc.language.isoenen
dc.subjectCultured Tumour Cellsen
dc.subjectLeukaemiaen
dc.subject.meshBone Marrow Transplantation-
dc.subject.meshHumans-
dc.subject.meshLeukemia, Myelogenous, Chronic, BCR-ABL Positive-
dc.subject.meshPhiladelphia Chromosome-
dc.subject.meshTime Factors-
dc.subject.meshTumor Cells, Cultured-
dc.titleResidual Ph- cells in chronic myeloid leukemia: detection and usefulness.en
dc.typeArticleen
dc.contributor.departmentDepartment of Experimental Hematology, Paterson Institute for Cancer Research, Christie Hospital, Manchester, United Kingdom.en
dc.identifier.journalStem Cellsen

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