The value of exfoliative cytology in the diagnosis of rectal malignancy.

2.50
Hdl Handle:
http://hdl.handle.net/10541/99775
Title:
The value of exfoliative cytology in the diagnosis of rectal malignancy.
Authors:
Wilson, Malcolm S; El Teraifi, Hassan; Schofield, Philip F
Abstract:
This study has assessed the feasibility and reliability of cytology smears taken from patients with known rectal carcinomas without the use of any special instruments. In a pilot study of 23 patients who all had proved rectal cancer, 19 patients had satisfactory smears, one of which produced a false negative result. The remaining 18 displayed varying degrees of dysplasia (10) or frank malignancy (8). One of the patients with a smear containing severely dysplastic cells had a negative biopsy but had clear clinical and radiological evidence of a rectal tumour. Subsequently, a blind controlled study was undertaken on 29 patients with either carcinoma, proctitis or a normal rectum. All 29 sets of smears were of diagnostic quality and were correctly diagnosed as benign or malignant by the cytologist who had no knowledge of the clinical diagnosis. This is a rapid and simple diagnostic test which, if positive for malignancy, allows treatment to be planned at the first consultation. In combination with a forceps biopsy, the rate of positive diagnosis may be increased. A dysplastic smear adds to the level of clinical suspicion and confirms the need for biopsy of a lesion.
Affiliation:
Department of Surgery, Christie Hospital, Withington, Manchester, UK.
Citation:
The value of exfoliative cytology in the diagnosis of rectal malignancy. 1993, 8 (2):78-80 Int J Colorectal Dis
Journal:
International Journal of Colorectal Disease
Issue Date:
Jul-1993
URI:
http://hdl.handle.net/10541/99775
DOI:
10.1007/BF00299332
PubMed ID:
8409691
Type:
Article
Language:
en
ISSN:
0179-1958
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorWilson, Malcolm Sen
dc.contributor.authorEl Teraifi, Hassanen
dc.contributor.authorSchofield, Philip Fen
dc.date.accessioned2010-05-25T10:41:07Z-
dc.date.available2010-05-25T10:41:07Z-
dc.date.issued1993-07-
dc.identifier.citationThe value of exfoliative cytology in the diagnosis of rectal malignancy. 1993, 8 (2):78-80 Int J Colorectal Disen
dc.identifier.issn0179-1958-
dc.identifier.pmid8409691-
dc.identifier.doi10.1007/BF00299332-
dc.identifier.urihttp://hdl.handle.net/10541/99775-
dc.description.abstractThis study has assessed the feasibility and reliability of cytology smears taken from patients with known rectal carcinomas without the use of any special instruments. In a pilot study of 23 patients who all had proved rectal cancer, 19 patients had satisfactory smears, one of which produced a false negative result. The remaining 18 displayed varying degrees of dysplasia (10) or frank malignancy (8). One of the patients with a smear containing severely dysplastic cells had a negative biopsy but had clear clinical and radiological evidence of a rectal tumour. Subsequently, a blind controlled study was undertaken on 29 patients with either carcinoma, proctitis or a normal rectum. All 29 sets of smears were of diagnostic quality and were correctly diagnosed as benign or malignant by the cytologist who had no knowledge of the clinical diagnosis. This is a rapid and simple diagnostic test which, if positive for malignancy, allows treatment to be planned at the first consultation. In combination with a forceps biopsy, the rate of positive diagnosis may be increased. A dysplastic smear adds to the level of clinical suspicion and confirms the need for biopsy of a lesion.en
dc.language.isoenen
dc.subjectRectal Canceren
dc.subject.meshAdenocarcinoma-
dc.subject.meshCytodiagnosis-
dc.subject.meshEvaluation Studies as Topic-
dc.subject.meshFeasibility Studies-
dc.subject.meshHumans-
dc.subject.meshProctitis-
dc.subject.meshRectal Neoplasms-
dc.subject.meshRectum-
dc.titleThe value of exfoliative cytology in the diagnosis of rectal malignancy.en
dc.typeArticleen
dc.contributor.departmentDepartment of Surgery, Christie Hospital, Withington, Manchester, UK.en
dc.identifier.journalInternational Journal of Colorectal Diseaseen

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