Volunteers or victims: patients' views of randomised cancer clinical trials.

2.50
Hdl Handle:
http://hdl.handle.net/10541/99258
Title:
Volunteers or victims: patients' views of randomised cancer clinical trials.
Authors:
Slevin, M; Mossman, J; Bowling, A; Leonard, R; Steward, William P; Harper, P; McIllmurray, M; Thatcher, Nick
Abstract:
Randomised clinical trials are essential for the objective evaluation of different treatment strategies in cancer. However, in the field of oncology, very few of the eligible patients are entered into trials, and most treatments have only been tested on a small percentage of patients. For doctors, a major deterrent to participating in trials is the lack of resources--particularly time, but often also the local facilities. This report suggests that patients themselves are willing to take part in clinical research, and are attracted by being treated by a doctor with a specialist interest in the disease and encouraged by the possibility that their progress will be monitored closely. With the recent NHS changes, it is timely for the Department of Health and other national health departments to consider carefully what can be done to ensure that no new treatments are adopted without effective evaluation. This will require departments of health to identify and implement ways to facilitate accrual of appropriate numbers of patients onto research protocols (whether non-randomised phase I or phase II studies or large, multicentre phase III trials) over short time periods.
Affiliation:
Department of Medical Oncology, St Bartholomew's Hospital, West Smithfield, London, UK.
Citation:
Volunteers or victims: patients' views of randomised cancer clinical trials. 1995, 71 (6):1270-4 Br. J. Cancer
Journal:
British Journal of Cancer
Issue Date:
Jun-1995
URI:
http://hdl.handle.net/10541/99258
PubMed ID:
7779722
Type:
Article
Language:
en
ISSN:
0007-0920
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorSlevin, Men
dc.contributor.authorMossman, Jen
dc.contributor.authorBowling, Aen
dc.contributor.authorLeonard, Ren
dc.contributor.authorSteward, William Pen
dc.contributor.authorHarper, Pen
dc.contributor.authorMcIllmurray, Men
dc.contributor.authorThatcher, Nicken
dc.date.accessioned2010-05-19T09:48:52Z-
dc.date.available2010-05-19T09:48:52Z-
dc.date.issued1995-06-
dc.identifier.citationVolunteers or victims: patients' views of randomised cancer clinical trials. 1995, 71 (6):1270-4 Br. J. Canceren
dc.identifier.issn0007-0920-
dc.identifier.pmid7779722-
dc.identifier.urihttp://hdl.handle.net/10541/99258-
dc.description.abstractRandomised clinical trials are essential for the objective evaluation of different treatment strategies in cancer. However, in the field of oncology, very few of the eligible patients are entered into trials, and most treatments have only been tested on a small percentage of patients. For doctors, a major deterrent to participating in trials is the lack of resources--particularly time, but often also the local facilities. This report suggests that patients themselves are willing to take part in clinical research, and are attracted by being treated by a doctor with a specialist interest in the disease and encouraged by the possibility that their progress will be monitored closely. With the recent NHS changes, it is timely for the Department of Health and other national health departments to consider carefully what can be done to ensure that no new treatments are adopted without effective evaluation. This will require departments of health to identify and implement ways to facilitate accrual of appropriate numbers of patients onto research protocols (whether non-randomised phase I or phase II studies or large, multicentre phase III trials) over short time periods.en
dc.language.isoenen
dc.subjectCanceren
dc.subject.meshAdolescent-
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshClinical Trials, Phase II as Topic-
dc.subject.meshClinical Trials, Phase III as Topic-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNeoplasms-
dc.subject.meshPatient Selection-
dc.subject.meshPatients-
dc.subject.meshPilot Projects-
dc.subject.meshQuestionnaires-
dc.subject.meshRandomized Controlled Trials as Topic-
dc.subject.meshResearch Subjects-
dc.subject.meshResource Allocation-
dc.subject.meshRisk Assessment-
dc.titleVolunteers or victims: patients' views of randomised cancer clinical trials.en
dc.typeArticleen
dc.contributor.departmentDepartment of Medical Oncology, St Bartholomew's Hospital, West Smithfield, London, UK.en
dc.identifier.journalBritish Journal of Canceren

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