Validation of a model to predict survival in elderly patients with acute myeloid leukaemia.

2.50
Hdl Handle:
http://hdl.handle.net/10541/99142
Title:
Validation of a model to predict survival in elderly patients with acute myeloid leukaemia.
Authors:
Johnson, Peter R; Ryder, W David J; Yin, J A
Abstract:
Intensive chemotherapy is the treatment of choice for selected elderly patients with acute myeloid leukaemia (AML). We recently developed a model to predict survival, thereby providing objective information upon which to select appropriate therapy for such patients. Such models, however, must be validated on a cohort of patients not used during the development of the model. We have tested the model using a series of 61 elderly patients consecutively treated with intensive chemotherapy. Using several statistical techniques, we have shown that the model is of value in predicting prognosis, though two patients did markedly better than the model prediction. This model may be useful for predicting survival in elderly patients with AML and warrants more extensive validation.
Affiliation:
Department of Haematology, Christie Hospital, Manchester.
Citation:
Validation of a model to predict survival in elderly patients with acute myeloid leukaemia. 1995, 90 (4):954-6 Br. J. Haematol.
Journal:
British Journal of Haematology
Issue Date:
Aug-1995
URI:
http://hdl.handle.net/10541/99142
DOI:
10.1111/j.1365-2141.1995.tb05224.x
PubMed ID:
7669679
Type:
Article
Language:
en
ISSN:
0007-1048
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorJohnson, Peter Ren
dc.contributor.authorRyder, W David Jen
dc.contributor.authorYin, J Aen
dc.date.accessioned2010-05-18T15:40:42Z-
dc.date.available2010-05-18T15:40:42Z-
dc.date.issued1995-08-
dc.identifier.citationValidation of a model to predict survival in elderly patients with acute myeloid leukaemia. 1995, 90 (4):954-6 Br. J. Haematol.en
dc.identifier.issn0007-1048-
dc.identifier.pmid7669679-
dc.identifier.doi10.1111/j.1365-2141.1995.tb05224.x-
dc.identifier.urihttp://hdl.handle.net/10541/99142-
dc.description.abstractIntensive chemotherapy is the treatment of choice for selected elderly patients with acute myeloid leukaemia (AML). We recently developed a model to predict survival, thereby providing objective information upon which to select appropriate therapy for such patients. Such models, however, must be validated on a cohort of patients not used during the development of the model. We have tested the model using a series of 61 elderly patients consecutively treated with intensive chemotherapy. Using several statistical techniques, we have shown that the model is of value in predicting prognosis, though two patients did markedly better than the model prediction. This model may be useful for predicting survival in elderly patients with AML and warrants more extensive validation.en
dc.language.isoenen
dc.subjectMyeloid Leukaemiaen
dc.subject.meshAcute Disease-
dc.subject.meshAged-
dc.subject.meshCohort Studies-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshLeukemia, Myeloid-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshModels, Statistical-
dc.subject.meshPredictive Value of Tests-
dc.subject.meshPrognosis-
dc.subject.meshSurvival Analysis-
dc.titleValidation of a model to predict survival in elderly patients with acute myeloid leukaemia.en
dc.typeArticleen
dc.contributor.departmentDepartment of Haematology, Christie Hospital, Manchester.en
dc.identifier.journalBritish Journal of Haematologyen

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.