Affiliation
CRC Department of Experimental Radiation Oncology, Paterson Institute for Cancer Research, Christie Hospital (NHS) Trust, Manchester, UK.Issue Date
1995-03
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Show full item recordAbstract
Cell death after irradiation occurs by apoptosis in certain cell populations in tissues. The phenomenon also occurs after high linear energy transfer (LET) irradiation, and the relative biological effectiveness (RBE) is 3 to 4 (with respect to low-LET radiation and apoptosis in intestinal crypts) for neutrons with energies of 14 MeV and up to 600 MeV. It is thought that p53 plays a role in the phenomenon, as radiation-induced apoptosis is not observed in p53-null animals.Citation
Apoptosis induced by high- and low-LET radiations. 1995, 34 (1):59-62 Radiat Environ BiophysJournal
Radiation and Environmental BiophysicsDOI
10.1007/BF01210548PubMed ID
7604163Type
ArticleLanguage
enISSN
0301-634Xae974a485f413a2113503eed53cd6c53
10.1007/BF01210548
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