2.50
Hdl Handle:
http://hdl.handle.net/10541/97399
Title:
CD34 cell separation: from basic research to clinical applications.
Authors:
Nadali, Gianpaolo; De Wynter, Erika A; Testa, Nydia G
Abstract:
Advances in the immunological identification of primitive haematopoietic cells have led to the development of various techniques for their characterisation and purification. The expression of the CD34 antigen by the stem cell compartment has been exploited for these purposes. Separation systems capable of isolating CD34+ cells on a large scale are finding use in the clinic. Areas of interest overlap for both researchers and clinicians, and efforts to mobilise, characterise, purify and transplant these cells continue. Different CD34 purification systems are reviewed, focusing on their possible applications in different research fields. Clinical results of CD34+ selection and the possible future applications of this technology in the clinic are also reported.
Affiliation:
CRC Department of Experimental Haematology, Paterson Institute for Cancer Research, Manchester, UK.
Citation:
CD34 cell separation: from basic research to clinical applications. 1995, 25 (3):121-7 Int. J. Clin. Lab. Res.
Journal:
International Journal of Clinical & Laboratory Research
Issue Date:
1995
URI:
http://hdl.handle.net/10541/97399
PubMed ID:
8562973
Type:
Article
Language:
en
ISSN:
0940-5437
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorNadali, Gianpaoloen
dc.contributor.authorDe Wynter, Erika Aen
dc.contributor.authorTesta, Nydia Gen
dc.date.accessioned2010-04-26T13:57:27Z-
dc.date.available2010-04-26T13:57:27Z-
dc.date.issued1995-
dc.identifier.citationCD34 cell separation: from basic research to clinical applications. 1995, 25 (3):121-7 Int. J. Clin. Lab. Res.en
dc.identifier.issn0940-5437-
dc.identifier.pmid8562973-
dc.identifier.urihttp://hdl.handle.net/10541/97399-
dc.description.abstractAdvances in the immunological identification of primitive haematopoietic cells have led to the development of various techniques for their characterisation and purification. The expression of the CD34 antigen by the stem cell compartment has been exploited for these purposes. Separation systems capable of isolating CD34+ cells on a large scale are finding use in the clinic. Areas of interest overlap for both researchers and clinicians, and efforts to mobilise, characterise, purify and transplant these cells continue. Different CD34 purification systems are reviewed, focusing on their possible applications in different research fields. Clinical results of CD34+ selection and the possible future applications of this technology in the clinic are also reported.en
dc.language.isoenen
dc.subject.meshAntigens, CD34-
dc.subject.meshCell Separation-
dc.subject.meshHumans-
dc.subject.meshStem Cell Transplantation-
dc.subject.meshStem Cells-
dc.titleCD34 cell separation: from basic research to clinical applications.en
dc.typeArticleen
dc.contributor.departmentCRC Department of Experimental Haematology, Paterson Institute for Cancer Research, Manchester, UK.en
dc.identifier.journalInternational Journal of Clinical & Laboratory Researchen

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