2.50
Hdl Handle:
http://hdl.handle.net/10541/96974
Title:
A transcribed polymorphism and sub-localisation of MDM2.
Authors:
Heighway, Jim; Mitchell, Erika L D; Jones, David R; White, Gavin R M; Santibanez-Koref, Mauro F
Abstract:
An NlaIV polymorphism in the 5' untranslated region of the MDM2 gene is described. MDM2 was sublocalised by fluorescence in situ hybridisation with a yeast artificial chromosome probe to 12q14.3-12q15. We demonstrate the use of the polymorphism to assess allelic imbalance in breast tumours.
Affiliation:
CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Christie CRC Research Centre, Manchester, UK.
Citation:
A transcribed polymorphism and sub-localisation of MDM2. 1994, 93 (5):611-2 Hum. Genet.
Journal:
Human Genetics
Issue Date:
May-1994
URI:
http://hdl.handle.net/10541/96974
DOI:
10.1007/BF00202837
PubMed ID:
8168847
Type:
Article
Language:
en
ISSN:
0340-6717
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorHeighway, Jimen
dc.contributor.authorMitchell, Erika L Den
dc.contributor.authorJones, David Ren
dc.contributor.authorWhite, Gavin R Men
dc.contributor.authorSantibanez-Koref, Mauro Fen
dc.date.accessioned2010-04-21T08:57:47Z-
dc.date.available2010-04-21T08:57:47Z-
dc.date.issued1994-05-
dc.identifier.citationA transcribed polymorphism and sub-localisation of MDM2. 1994, 93 (5):611-2 Hum. Genet.en
dc.identifier.issn0340-6717-
dc.identifier.pmid8168847-
dc.identifier.doi10.1007/BF00202837-
dc.identifier.urihttp://hdl.handle.net/10541/96974-
dc.description.abstractAn NlaIV polymorphism in the 5' untranslated region of the MDM2 gene is described. MDM2 was sublocalised by fluorescence in situ hybridisation with a yeast artificial chromosome probe to 12q14.3-12q15. We demonstrate the use of the polymorphism to assess allelic imbalance in breast tumours.en
dc.language.isoenen
dc.subjectBreast Canceren
dc.subjectCancer Proteinsen
dc.subject.meshAlleles-
dc.subject.meshBase Sequence-
dc.subject.meshBreast Neoplasms-
dc.subject.meshDNA Primers-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshIn Situ Hybridization, Fluorescence-
dc.subject.meshMolecular Sequence Data-
dc.subject.meshNeoplasm Proteins-
dc.subject.meshNuclear Proteins-
dc.subject.meshPolymerase Chain Reaction-
dc.subject.meshPolymorphism, Genetic-
dc.subject.meshProto-Oncogene Proteins-
dc.subject.meshProto-Oncogene Proteins c-mdm2-
dc.subject.meshSaccharomyces cerevisiae-
dc.titleA transcribed polymorphism and sub-localisation of MDM2.en
dc.typeArticleen
dc.contributor.departmentCRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Christie CRC Research Centre, Manchester, UK.en
dc.identifier.journalHuman Geneticsen

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