A B cell specific immediate early human gene is located on chromosome band 1q31 and encodes an alpha helical basic phosphoprotein.

2.50
Hdl Handle:
http://hdl.handle.net/10541/96961
Title:
A B cell specific immediate early human gene is located on chromosome band 1q31 and encodes an alpha helical basic phosphoprotein.
Authors:
Newton, J S; Deed, Richard W; Mitchell, Erika L D; Murphy, J J; Norton, John D
Abstract:
We have determined the cDNA sequence of a human B cell specific, immediate early gene, designated 1R20, which is inducible in response to several B cell activation signals. The cDNA sequence predicts a 196 amino acid open reading frame comprising numerous highly basic residues and the predicted structure contains several potential alpha helical domains together with eight consensus protein phosphorylation sites. The 1R20 gene has been localised by fluorescence in situ hybridisation to chromosome band 1q31, a region known to be implicated in the pathogenesis of haemopoietic malignancies.
Affiliation:
Immunology Section, Kings College London, UK.
Citation:
A B cell specific immediate early human gene is located on chromosome band 1q31 and encodes an alpha helical basic phosphoprotein. 1993, 1216 (2):314-6 Biochim. Biophys. Acta
Journal:
Biochimica et Biophysica Acta
Issue Date:
16-Nov-1993
URI:
http://hdl.handle.net/10541/96961
PubMed ID:
8241276
Type:
Article
Language:
en
ISSN:
0006-3002
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorNewton, J Sen
dc.contributor.authorDeed, Richard Wen
dc.contributor.authorMitchell, Erika L Den
dc.contributor.authorMurphy, J Jen
dc.contributor.authorNorton, John Den
dc.date.accessioned2010-04-21T09:07:08Z-
dc.date.available2010-04-21T09:07:08Z-
dc.date.issued1993-11-16-
dc.identifier.citationA B cell specific immediate early human gene is located on chromosome band 1q31 and encodes an alpha helical basic phosphoprotein. 1993, 1216 (2):314-6 Biochim. Biophys. Actaen
dc.identifier.issn0006-3002-
dc.identifier.pmid8241276-
dc.identifier.urihttp://hdl.handle.net/10541/96961-
dc.description.abstractWe have determined the cDNA sequence of a human B cell specific, immediate early gene, designated 1R20, which is inducible in response to several B cell activation signals. The cDNA sequence predicts a 196 amino acid open reading frame comprising numerous highly basic residues and the predicted structure contains several potential alpha helical domains together with eight consensus protein phosphorylation sites. The 1R20 gene has been localised by fluorescence in situ hybridisation to chromosome band 1q31, a region known to be implicated in the pathogenesis of haemopoietic malignancies.en
dc.language.isoenen
dc.subject.meshAmino Acid Sequence-
dc.subject.meshB-Lymphocytes-
dc.subject.meshBase Sequence-
dc.subject.meshBinding Sites-
dc.subject.meshChromosomes, Human, Pair 1-
dc.subject.meshConserved Sequence-
dc.subject.meshDNA, Complementary-
dc.subject.meshGenes, Immediate-Early-
dc.subject.meshHumans-
dc.subject.meshImmediate-Early Proteins-
dc.subject.meshLymphoma, B-Cell-
dc.subject.meshMolecular Sequence Data-
dc.subject.meshPhosphoproteins-
dc.subject.meshRGS Proteins-
dc.titleA B cell specific immediate early human gene is located on chromosome band 1q31 and encodes an alpha helical basic phosphoprotein.en
dc.typeArticleen
dc.contributor.departmentImmunology Section, Kings College London, UK.en
dc.identifier.journalBiochimica et Biophysica Actaen
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