Clinical significance of the tumour capsule in the treatment of parotid pleomorphic adenomas.

2.50
Hdl Handle:
http://hdl.handle.net/10541/96039
Title:
Clinical significance of the tumour capsule in the treatment of parotid pleomorphic adenomas.
Authors:
McGurk, M; Renehan, Andrew G; Gleave, E N; Hancock, B D
Abstract:
The propensity of pleomorphic adenomas to recur is generally attributed to the biological nature of the tumour, and surgery close to the capsule is perceived as undesirable. At the Christie Hospital, Manchester, between 1947 and 1992, 475 tumours arising within the superficial portion of the parotid gland were treated by two surgical techniques: extracapsular dissection (380 patients) and superficial parotidectomy (95). Recurrence rates were 2 per cent in each group (median follow-up 12.5 years). Contact of the tumour with the facial nerve was recorded in 51 per cent of patients. There was no difference between the treatment groups in the incidence of permanent facial nerve injury (2 versus 1 per cent respectively). This study demonstrates that dissection in close proximity to the tumour is possible without inducing recurrence and that in practice the microinvasion of the capsule by tumour buds has limited clinical significance.
Affiliation:
Department of Oral and Maxillofacial Surgery, UMDS, Guy's Hospital, London, UK.
Citation:
Clinical significance of the tumour capsule in the treatment of parotid pleomorphic adenomas. 1996, 83 (12):1747-9 Br J Surg
Journal:
The British Journal of surgery
Issue Date:
Dec-1996
URI:
http://hdl.handle.net/10541/96039
DOI:
10.1002/bjs.1800831227
PubMed ID:
9038558
Type:
Article
Language:
en
ISSN:
0007-1323
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMcGurk, Men
dc.contributor.authorRenehan, Andrew Gen
dc.contributor.authorGleave, E Nen
dc.contributor.authorHancock, B Den
dc.date.accessioned2010-04-08T15:49:58Z-
dc.date.available2010-04-08T15:49:58Z-
dc.date.issued1996-12-
dc.identifier.citationClinical significance of the tumour capsule in the treatment of parotid pleomorphic adenomas. 1996, 83 (12):1747-9 Br J Surgen
dc.identifier.issn0007-1323-
dc.identifier.pmid9038558-
dc.identifier.doi10.1002/bjs.1800831227-
dc.identifier.urihttp://hdl.handle.net/10541/96039-
dc.description.abstractThe propensity of pleomorphic adenomas to recur is generally attributed to the biological nature of the tumour, and surgery close to the capsule is perceived as undesirable. At the Christie Hospital, Manchester, between 1947 and 1992, 475 tumours arising within the superficial portion of the parotid gland were treated by two surgical techniques: extracapsular dissection (380 patients) and superficial parotidectomy (95). Recurrence rates were 2 per cent in each group (median follow-up 12.5 years). Contact of the tumour with the facial nerve was recorded in 51 per cent of patients. There was no difference between the treatment groups in the incidence of permanent facial nerve injury (2 versus 1 per cent respectively). This study demonstrates that dissection in close proximity to the tumour is possible without inducing recurrence and that in practice the microinvasion of the capsule by tumour buds has limited clinical significance.en
dc.language.isoenen
dc.subjectCancer Recurrenceen
dc.subjectParotid Canceren
dc.subject.meshAdenoma, Pleomorphic-
dc.subject.meshAdolescent-
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshChild-
dc.subject.meshChild, Preschool-
dc.subject.meshDissection-
dc.subject.meshFollow-Up Studies-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNeoplasm Recurrence, Local-
dc.subject.meshParotid Neoplasms-
dc.titleClinical significance of the tumour capsule in the treatment of parotid pleomorphic adenomas.en
dc.typeArticleen
dc.contributor.departmentDepartment of Oral and Maxillofacial Surgery, UMDS, Guy's Hospital, London, UK.en
dc.identifier.journalThe British Journal of surgeryen

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