Neurosurgery in a patient with Creutzfeldt-Jakob disease after pituitary derived growth hormone therapy in childhood.

2.50
Hdl Handle:
http://hdl.handle.net/10541/95993
Title:
Neurosurgery in a patient with Creutzfeldt-Jakob disease after pituitary derived growth hormone therapy in childhood.
Authors:
Holmes, Sarah J; Ironside, J W; Shalet, Stephen M
Abstract:
The case of a young man who had previously received pituitary derived growth hormone for treatment of radiation induced growth hormone deficiency is reported. He underwent neurosurgery for presumed recurrence of a posterior fossa tumour but was subsequently shown to have Creutzfeldt-Jakob disease, confirmed on necropsy. The risk of transmission of Creutzfeldt-Jakob disease by neurosurgical instruments is discussed. Since the occurrence of this case the Department of Health have issued guidelines concerning neurosurgery and ophthalmic surgery in patients who have previously received treatment with pituitary derived growth hormone and may therefore be at risk of developing Creutzfeldt-Jakob disease. Surgical instruments used on such patients should under no circumstances be reused, and should be destroyed after use.
Affiliation:
Department of Endocrinology, Christie Hospital NHS Trust, Manchester, UK.
Citation:
Neurosurgery in a patient with Creutzfeldt-Jakob disease after pituitary derived growth hormone therapy in childhood. 1996, 60 (3):333-5 J. Neurol. Neurosurg. Psychiatr.
Journal:
Journal of Neurology, Neurosurgery, and Psychiatry
Issue Date:
Mar-1996
URI:
http://hdl.handle.net/10541/95993
DOI:
10.1136/jnnp.60.3.333
PubMed ID:
8609514
Type:
Article
Language:
en
ISSN:
0022-3050
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorHolmes, Sarah Jen
dc.contributor.authorIronside, J Wen
dc.contributor.authorShalet, Stephen Men
dc.date.accessioned2010-04-08T11:40:38Z-
dc.date.available2010-04-08T11:40:38Z-
dc.date.issued1996-03-
dc.identifier.citationNeurosurgery in a patient with Creutzfeldt-Jakob disease after pituitary derived growth hormone therapy in childhood. 1996, 60 (3):333-5 J. Neurol. Neurosurg. Psychiatr.en
dc.identifier.issn0022-3050-
dc.identifier.pmid8609514-
dc.identifier.doi10.1136/jnnp.60.3.333-
dc.identifier.urihttp://hdl.handle.net/10541/95993-
dc.description.abstractThe case of a young man who had previously received pituitary derived growth hormone for treatment of radiation induced growth hormone deficiency is reported. He underwent neurosurgery for presumed recurrence of a posterior fossa tumour but was subsequently shown to have Creutzfeldt-Jakob disease, confirmed on necropsy. The risk of transmission of Creutzfeldt-Jakob disease by neurosurgical instruments is discussed. Since the occurrence of this case the Department of Health have issued guidelines concerning neurosurgery and ophthalmic surgery in patients who have previously received treatment with pituitary derived growth hormone and may therefore be at risk of developing Creutzfeldt-Jakob disease. Surgical instruments used on such patients should under no circumstances be reused, and should be destroyed after use.en
dc.language.isoenen
dc.subjectCerebellar Canceren
dc.subject.meshAstrocytoma-
dc.subject.meshCerebellar Neoplasms-
dc.subject.meshChild-
dc.subject.meshCreutzfeldt-Jakob Syndrome-
dc.subject.meshDrug Contamination-
dc.subject.meshEquipment Contamination-
dc.subject.meshFatal Outcome-
dc.subject.meshGrowth Disorders-
dc.subject.meshGrowth Hormone-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshPostoperative Complications-
dc.titleNeurosurgery in a patient with Creutzfeldt-Jakob disease after pituitary derived growth hormone therapy in childhood.en
dc.typeArticleen
dc.contributor.departmentDepartment of Endocrinology, Christie Hospital NHS Trust, Manchester, UK.en
dc.identifier.journalJournal of Neurology, Neurosurgery, and Psychiatryen

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