2.50
Hdl Handle:
http://hdl.handle.net/10541/95966
Title:
Malignant melanoma showing smooth muscle differentiation.
Authors:
Banerjee, Saumitra S; Bishop, P W; Nicholson, C M; Eyden, Brian P
Abstract:
A unique case of a metastatic non-desmoplastic sarcomatoid malignant melanoma in an axillary lymph node showing smooth muscle differentiation in a 54 year old woman is described. The tumour cells exhibited alpha-smooth muscle actin, HHF-35 and desmin positivity but were negative for S100 protein and HMB-45. Ultrastructural examination revealed smooth muscle phenotype and there was no evidence of myofibroblastic differentiation, a feature described previously in desmoplastic melanomas.
Affiliation:
Department of Pathology, Christie Hospital, Manchester.
Citation:
Malignant melanoma showing smooth muscle differentiation. 1996, 49 (11):950-1 J. Clin. Pathol.
Journal:
Journal of Clinical Pathology
Issue Date:
Nov-1996
URI:
http://hdl.handle.net/10541/95966
DOI:
10.1136/jcp.49.11.950
PubMed ID:
8944620
Type:
Article
Language:
en
ISSN:
0021-9746
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorBanerjee, Saumitra Sen
dc.contributor.authorBishop, P Wen
dc.contributor.authorNicholson, C Men
dc.contributor.authorEyden, Brian Pen
dc.date.accessioned2010-04-08T11:51:43Z-
dc.date.available2010-04-08T11:51:43Z-
dc.date.issued1996-11-
dc.identifier.citationMalignant melanoma showing smooth muscle differentiation. 1996, 49 (11):950-1 J. Clin. Pathol.en
dc.identifier.issn0021-9746-
dc.identifier.pmid8944620-
dc.identifier.doi10.1136/jcp.49.11.950-
dc.identifier.urihttp://hdl.handle.net/10541/95966-
dc.description.abstractA unique case of a metastatic non-desmoplastic sarcomatoid malignant melanoma in an axillary lymph node showing smooth muscle differentiation in a 54 year old woman is described. The tumour cells exhibited alpha-smooth muscle actin, HHF-35 and desmin positivity but were negative for S100 protein and HMB-45. Ultrastructural examination revealed smooth muscle phenotype and there was no evidence of myofibroblastic differentiation, a feature described previously in desmoplastic melanomas.en
dc.language.isoenen
dc.subject.meshActins-
dc.subject.meshDesmin-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshImmunohistochemistry-
dc.subject.meshLymphatic Metastasis-
dc.subject.meshMelanoma-
dc.subject.meshMiddle Aged-
dc.titleMalignant melanoma showing smooth muscle differentiation.en
dc.typeArticleen
dc.contributor.departmentDepartment of Pathology, Christie Hospital, Manchester.en
dc.identifier.journalJournal of Clinical Pathologyen

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.