Malignant peripheral nerve sheath tumour with vascular differentiation: a report of four cases.

2.50
Hdl Handle:
http://hdl.handle.net/10541/95965
Title:
Malignant peripheral nerve sheath tumour with vascular differentiation: a report of four cases.
Authors:
Morphopoulos, G D; Banerjee, Saumitra S; Ali, H H; Stewart, M; Vasudev, K S; Eyden, Brian P; Harris, Martin
Abstract:
Four cases of malignant peripheral nerve sheath tumour showing vascular differentiation are described. One case was associated with neurofibromatosis 1 and contained angiosarcomatous, cartilaginous and rhabdomyoblastic elements. The other cases occurred in patients without neurofibromatosis and showed a spectrum of vascular lesions ranging from lobulated, haemangioma-like structures to angiosarcoma. These are the first recorded examples of this phenomenon not associated with neurofibromatosis. Immunohistochemical examination demonstrated the endothelial nature of the lesions in all cases and revealed cells positive for alpha-smooth muscle actin, probably pericytes, closely apposed to the endothelium.
Affiliation:
Department of Histopathology, Christie Hospital NHS Trust, Manchester, UK.
Citation:
Malignant peripheral nerve sheath tumour with vascular differentiation: a report of four cases. 1996, 28 (5):401-10 Histopathology
Journal:
Histopathology
Issue Date:
May-1996
URI:
http://hdl.handle.net/10541/95965
PubMed ID:
8735715
Type:
Article
Language:
en
ISSN:
0309-0167
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMorphopoulos, G Den
dc.contributor.authorBanerjee, Saumitra Sen
dc.contributor.authorAli, H Hen
dc.contributor.authorStewart, Men
dc.contributor.authorVasudev, K Sen
dc.contributor.authorEyden, Brian Pen
dc.contributor.authorHarris, Martinen
dc.date.accessioned2010-04-08T11:49:45Z-
dc.date.available2010-04-08T11:49:45Z-
dc.date.issued1996-05-
dc.identifier.citationMalignant peripheral nerve sheath tumour with vascular differentiation: a report of four cases. 1996, 28 (5):401-10 Histopathologyen
dc.identifier.issn0309-0167-
dc.identifier.pmid8735715-
dc.identifier.urihttp://hdl.handle.net/10541/95965-
dc.description.abstractFour cases of malignant peripheral nerve sheath tumour showing vascular differentiation are described. One case was associated with neurofibromatosis 1 and contained angiosarcomatous, cartilaginous and rhabdomyoblastic elements. The other cases occurred in patients without neurofibromatosis and showed a spectrum of vascular lesions ranging from lobulated, haemangioma-like structures to angiosarcoma. These are the first recorded examples of this phenomenon not associated with neurofibromatosis. Immunohistochemical examination demonstrated the endothelial nature of the lesions in all cases and revealed cells positive for alpha-smooth muscle actin, probably pericytes, closely apposed to the endothelium.en
dc.language.isoenen
dc.subjectHaemangiomaen
dc.subjectHaemangiosarcomaen
dc.subjectSecond Primary Canceren
dc.subjectNeuroectodermal Tumoursen
dc.subjectPeripheral Nervous System Canceren
dc.subjectVascular Canceren
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshCell Differentiation-
dc.subject.meshCell Transformation, Neoplastic-
dc.subject.meshEndothelium, Vascular-
dc.subject.meshFemale-
dc.subject.meshHemangioma-
dc.subject.meshHemangiosarcoma-
dc.subject.meshHumans-
dc.subject.meshImmunohistochemistry-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNeoplasms, Second Primary-
dc.subject.meshNeurilemmoma-
dc.subject.meshNeuroectodermal Tumors, Primitive, Peripheral-
dc.subject.meshNeurofibromatosis 1-
dc.subject.meshPeripheral Nervous System Neoplasms-
dc.subject.meshVascular Neoplasms-
dc.titleMalignant peripheral nerve sheath tumour with vascular differentiation: a report of four cases.en
dc.typeArticleen
dc.contributor.departmentDepartment of Histopathology, Christie Hospital NHS Trust, Manchester, UK.en
dc.identifier.journalHistopathologyen
All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.