2.50
Hdl Handle:
http://hdl.handle.net/10541/95920
Title:
Primary small cell neuroendocrine carcinoma of the kidney.
Authors:
Morgan, K G; Banerjee, Saumitra S; Eyden, Brian P; Barnard, R J
Abstract:
The histological, immunohistochemical, and ultrastructural features of a primary small cell neuroendocrine carcinoma of the renal parenchyma are described. Tumor cells were positive for cytokeratin, neuron-specific enolase, and Leu 7, but Grimelius- and chromogranin-negative. They also exhibited positivity with anti-MIC2 antibody. By electron microscopy, tonofibrils, primitive desmosomes, and dense-core granules with a neuroendocrine appearance were present. This is only the 7th recorded example of such a tumor at this site, which showed an aggressive course characterized by widespread bony metastases.
Affiliation:
Department of Pathology, Christie Hospital NHS Trust, Manchester, United Kingdom.
Citation:
Primary small cell neuroendocrine carcinoma of the kidney., 20 (2):141-4 Ultrastruct Pathol
Journal:
Ultrastructural Pathology
Issue Date:
7-Apr-2010
URI:
http://hdl.handle.net/10541/95920
DOI:
10.3109/01913129609016308
PubMed ID:
8882359
Type:
Article
Language:
en
ISSN:
0191-3123
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMorgan, K Gen
dc.contributor.authorBanerjee, Saumitra Sen
dc.contributor.authorEyden, Brian Pen
dc.contributor.authorBarnard, R Jen
dc.date.accessioned2010-04-07T15:30:09Z-
dc.date.available2010-04-07T15:30:09Z-
dc.date.issued2010-04-07T15:30:09Z-
dc.identifier.citationPrimary small cell neuroendocrine carcinoma of the kidney., 20 (2):141-4 Ultrastruct Patholen
dc.identifier.issn0191-3123-
dc.identifier.pmid8882359-
dc.identifier.doi10.3109/01913129609016308-
dc.identifier.urihttp://hdl.handle.net/10541/95920-
dc.description.abstractThe histological, immunohistochemical, and ultrastructural features of a primary small cell neuroendocrine carcinoma of the renal parenchyma are described. Tumor cells were positive for cytokeratin, neuron-specific enolase, and Leu 7, but Grimelius- and chromogranin-negative. They also exhibited positivity with anti-MIC2 antibody. By electron microscopy, tonofibrils, primitive desmosomes, and dense-core granules with a neuroendocrine appearance were present. This is only the 7th recorded example of such a tumor at this site, which showed an aggressive course characterized by widespread bony metastases.en
dc.language.isoenen
dc.subjectKidney Canceren
dc.subject.meshAdult-
dc.subject.meshAnimals-
dc.subject.meshCarcinoma, Neuroendocrine-
dc.subject.meshCarcinoma, Small Cell-
dc.subject.meshFatal Outcome-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshImmunohistochemistry-
dc.subject.meshKidney Neoplasms-
dc.subject.meshMice-
dc.titlePrimary small cell neuroendocrine carcinoma of the kidney.en
dc.typeArticleen
dc.contributor.departmentDepartment of Pathology, Christie Hospital NHS Trust, Manchester, United Kingdom.en
dc.identifier.journalUltrastructural Pathologyen

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