2.50
Hdl Handle:
http://hdl.handle.net/10541/95490
Title:
Uptake of genetic testing for cancer predisposition.
Authors:
Evans, D Gareth R; Maher, E R; Macleod, R; Davies, D R; Craufurd, D
Abstract:
Although there has been much debate about the uptake and effects of predictive testing for common cancers, such as breast and colon cancer, little has been published on the more classical tumour predisposing conditions, such as von Hippel-Lindau disease and familial adenomatous polyposis. Since 1990 the genetics departments in Manchester and Cambridge have had a genetic register for cancer predisposing syndromes and presymptomatic testing for these conditions has been offered once this has become possible. To investigate the factors that might influence uptake of genetic testing in familial cancer syndromes we have reviewed our experience. Demand for predictive testing has generally been high, but men had a lower uptake (77%) than a comparable group of women (93%) (p < 0.01).
Affiliation:
CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Christie Hospital, Manchester, UK.
Citation:
Uptake of genetic testing for cancer predisposition. 1997, 34 (9):746-8 J. Med. Genet.
Journal:
Journal of Medical Genetics
Issue Date:
Sep-1997
URI:
http://hdl.handle.net/10541/95490
DOI:
10.1136/jmg.34.9.746
PubMed ID:
9321761
Type:
Article
Language:
en
ISSN:
0022-2593
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorEvans, D Gareth Ren
dc.contributor.authorMaher, E Ren
dc.contributor.authorMacleod, Ren
dc.contributor.authorDavies, D Ren
dc.contributor.authorCraufurd, Den
dc.date.accessioned2010-04-01T14:20:02Z-
dc.date.available2010-04-01T14:20:02Z-
dc.date.issued1997-09-
dc.identifier.citationUptake of genetic testing for cancer predisposition. 1997, 34 (9):746-8 J. Med. Genet.en
dc.identifier.issn0022-2593-
dc.identifier.pmid9321761-
dc.identifier.doi10.1136/jmg.34.9.746-
dc.identifier.urihttp://hdl.handle.net/10541/95490-
dc.description.abstractAlthough there has been much debate about the uptake and effects of predictive testing for common cancers, such as breast and colon cancer, little has been published on the more classical tumour predisposing conditions, such as von Hippel-Lindau disease and familial adenomatous polyposis. Since 1990 the genetics departments in Manchester and Cambridge have had a genetic register for cancer predisposing syndromes and presymptomatic testing for these conditions has been offered once this has become possible. To investigate the factors that might influence uptake of genetic testing in familial cancer syndromes we have reviewed our experience. Demand for predictive testing has generally been high, but men had a lower uptake (77%) than a comparable group of women (93%) (p < 0.01).en
dc.language.isoenen
dc.subjectTumour Suppressor Protein p53en
dc.subject.meshAdenomatous Polyposis Coli-
dc.subject.meshAdolescent-
dc.subject.meshAdult-
dc.subject.meshAttitude to Health-
dc.subject.meshChild-
dc.subject.meshChild, Preschool-
dc.subject.meshFemale-
dc.subject.meshGenetic Counseling-
dc.subject.meshGenetic Testing-
dc.subject.meshGreat Britain-
dc.subject.meshHeterozygote-
dc.subject.meshHumans-
dc.subject.meshLi-Fraumeni Syndrome-
dc.subject.meshMale-
dc.subject.meshMutation-
dc.subject.meshNeurofibromatosis 2-
dc.subject.meshTumor Suppressor Protein p53-
dc.subject.meshvon Hippel-Lindau Disease-
dc.titleUptake of genetic testing for cancer predisposition.en
dc.typeArticleen
dc.contributor.departmentCRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Christie Hospital, Manchester, UK.en
dc.identifier.journalJournal of Medical Geneticsen

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.