Implications for immunosurveillance of altered HLA class I phenotypes in human tumours.

2.50
Hdl Handle:
http://hdl.handle.net/10541/95476
Title:
Implications for immunosurveillance of altered HLA class I phenotypes in human tumours.
Authors:
Garrido, F; Ruiz-Cabello, F; Cabrera, T; Pérez-Villar, J J; López-Botet, M; Duggan-Keen, M; Stern, Peter L
Abstract:
HLA class I downregulation is a frequent event associated with tumour invasion and development. Altered HLA class I tumour phenotypes can have profound effects on T-cell and natural killer (NK)-cell antitumour responses. Here, Federico Garrido and colleagues analyse these altered tumour phenotypes in detail, indicating their potential relevance for implementation of immunotherapeutic protocols and strategies to overcome tumour escape mechanisms.
Affiliation:
Dpto de Análisis Clinicos e Inmunología, Hospital Universitario Virgen de las Nieves, Universidad de Granada, Spain. Fgarrido@golialt. ugr.es
Citation:
Implications for immunosurveillance of altered HLA class I phenotypes in human tumours. 1997, 18 (2):89-95 Immunol. Today
Journal:
Immunology today
Issue Date:
Feb-1997
URI:
http://hdl.handle.net/10541/95476
DOI:
10.1016/S0167-5699(96)10075-X
PubMed ID:
9057360
Type:
Article
Language:
en
ISSN:
0167-5699
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorGarrido, Fen
dc.contributor.authorRuiz-Cabello, Fen
dc.contributor.authorCabrera, Ten
dc.contributor.authorPérez-Villar, J Jen
dc.contributor.authorLópez-Botet, Men
dc.contributor.authorDuggan-Keen, Men
dc.contributor.authorStern, Peter Len
dc.date.accessioned2010-04-01T13:31:10Z-
dc.date.available2010-04-01T13:31:10Z-
dc.date.issued1997-02-
dc.identifier.citationImplications for immunosurveillance of altered HLA class I phenotypes in human tumours. 1997, 18 (2):89-95 Immunol. Todayen
dc.identifier.issn0167-5699-
dc.identifier.pmid9057360-
dc.identifier.doi10.1016/S0167-5699(96)10075-X-
dc.identifier.urihttp://hdl.handle.net/10541/95476-
dc.description.abstractHLA class I downregulation is a frequent event associated with tumour invasion and development. Altered HLA class I tumour phenotypes can have profound effects on T-cell and natural killer (NK)-cell antitumour responses. Here, Federico Garrido and colleagues analyse these altered tumour phenotypes in detail, indicating their potential relevance for implementation of immunotherapeutic protocols and strategies to overcome tumour escape mechanisms.en
dc.language.isoenen
dc.subjectCanceren
dc.subject.meshHLA Antigens-
dc.subject.meshHistocompatibility Antigens Class I-
dc.subject.meshHumans-
dc.subject.meshImmunologic Surveillance-
dc.subject.meshImmunophenotyping-
dc.subject.meshNeoplasms-
dc.titleImplications for immunosurveillance of altered HLA class I phenotypes in human tumours.en
dc.typeArticleen
dc.contributor.departmentDpto de Análisis Clinicos e Inmunología, Hospital Universitario Virgen de las Nieves, Universidad de Granada, Spain. Fgarrido@golialt. ugr.esen
dc.identifier.journalImmunology todayen

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