Mapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16-->q21.

2.50
Hdl Handle:
http://hdl.handle.net/10541/95463
Title:
Mapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16-->q21.
Authors:
Morelli, C; Cardona, F; Boyle, John M; Negrini, M; Barbanti-Brodano, G
Abstract:
Twenty two expressed sequence tags (ESTs) have been mapped at the border of 6q16-->q21 and at the proximal end of 6q21, a candidate for two tumor suppressor genes and a senescence gene. Use of a translocation and deletion hybrid panel together with a 4-Mb YAC contig allowed us to precisely define the position of the ESTs. Thirteen ESTs were placed within the 4-Mb interval at the proximal portion of 6q21 using a restriction map of the YAC contig, seven ESTs span a 2-Mb region on the 6q16-->q21 border, and two are distal to the contig. Refinement of the localization of these ESTs will provide substantial assistance in identifying new genes within the region 6q16-->q21.
Affiliation:
Department of Experimental and Diagnostic Medicine, University of Ferrara, Italy.
Citation:
Mapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16-->q21. 1997, 79 (1-2):97-100 Cytogenet. Cell Genet.
Journal:
Cytogenetics and Cell Genetics
Issue Date:
1997
URI:
http://hdl.handle.net/10541/95463
DOI:
10.1159/000134691
PubMed ID:
9533021
Type:
Article
Language:
en
ISSN:
0301-0171
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorMorelli, Cen
dc.contributor.authorCardona, Fen
dc.contributor.authorBoyle, John Men
dc.contributor.authorNegrini, Men
dc.contributor.authorBarbanti-Brodano, Gen
dc.date.accessioned2010-04-01T11:05:44Z-
dc.date.available2010-04-01T11:05:44Z-
dc.date.issued1997-
dc.identifier.citationMapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16-->q21. 1997, 79 (1-2):97-100 Cytogenet. Cell Genet.en
dc.identifier.issn0301-0171-
dc.identifier.pmid9533021-
dc.identifier.doi10.1159/000134691-
dc.identifier.urihttp://hdl.handle.net/10541/95463-
dc.description.abstractTwenty two expressed sequence tags (ESTs) have been mapped at the border of 6q16-->q21 and at the proximal end of 6q21, a candidate for two tumor suppressor genes and a senescence gene. Use of a translocation and deletion hybrid panel together with a 4-Mb YAC contig allowed us to precisely define the position of the ESTs. Thirteen ESTs were placed within the 4-Mb interval at the proximal portion of 6q21 using a restriction map of the YAC contig, seven ESTs span a 2-Mb region on the 6q16-->q21 border, and two are distal to the contig. Refinement of the localization of these ESTs will provide substantial assistance in identifying new genes within the region 6q16-->q21.en
dc.language.isoenen
dc.subjectTumour Suppressor Genesen
dc.subject.meshAging-
dc.subject.meshChromosome Mapping-
dc.subject.meshChromosomes, Artificial, Yeast-
dc.subject.meshChromosomes, Human, Pair 6-
dc.subject.meshDNA Primers-
dc.subject.meshGene Deletion-
dc.subject.meshGenes, Tumor Suppressor-
dc.subject.meshGenetic Markers-
dc.subject.meshHumans-
dc.subject.meshTranslocation, Genetic-
dc.titleMapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16-->q21.en
dc.typeArticleen
dc.contributor.departmentDepartment of Experimental and Diagnostic Medicine, University of Ferrara, Italy.en
dc.identifier.journalCytogenetics and Cell Geneticsen

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