Relapse of intracranial germinoma 23 years postirradiation in a patient given growth hormone replacement.

2.50
Hdl Handle:
http://hdl.handle.net/10541/94690
Title:
Relapse of intracranial germinoma 23 years postirradiation in a patient given growth hormone replacement.
Authors:
Kiltie, Anne E; Collins, Conor D; Gattamaneni, Rao; Shalet, Stephen M
Abstract:
There is no clear evidence that growth hormone replacement therapy for treatment-related growth hormone deficiency in patients with childhood intracranial malignancies has a role in tumour relapse or second malignancy. A 16-year-old girl with an intracranial germinoma was treated with local radiotherapy and subsequently received growth hormone replacement therapy as an adult. Three years after starting growth hormone therapy, 23 years after her radiotherapy treatment, the patient's tumour recurred. Surveillance requirements for patients receiving growth hormone in this setting are discussed.
Affiliation:
Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, United Kingdom.
Citation:
Relapse of intracranial germinoma 23 years postirradiation in a patient given growth hormone replacement. 1997, 29 (1):41-4 Med. Pediatr. Oncol.
Journal:
Medical and Pediatric Oncology
Issue Date:
Jul-1997
URI:
http://hdl.handle.net/10541/94690
DOI:
10.1002/(SICI)1096-911X(199707)29:1<41::AID-MPO8>3.0.CO;2-S
PubMed ID:
9142205
Type:
Article
Language:
en
ISSN:
0098-1532
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorKiltie, Anne Een
dc.contributor.authorCollins, Conor Den
dc.contributor.authorGattamaneni, Raoen
dc.contributor.authorShalet, Stephen Men
dc.date.accessioned2010-03-23T15:04:52Z-
dc.date.available2010-03-23T15:04:52Z-
dc.date.issued1997-07-
dc.identifier.citationRelapse of intracranial germinoma 23 years postirradiation in a patient given growth hormone replacement. 1997, 29 (1):41-4 Med. Pediatr. Oncol.en
dc.identifier.issn0098-1532-
dc.identifier.pmid9142205-
dc.identifier.doi10.1002/(SICI)1096-911X(199707)29:1<41::AID-MPO8>3.0.CO;2-S-
dc.identifier.urihttp://hdl.handle.net/10541/94690-
dc.description.abstractThere is no clear evidence that growth hormone replacement therapy for treatment-related growth hormone deficiency in patients with childhood intracranial malignancies has a role in tumour relapse or second malignancy. A 16-year-old girl with an intracranial germinoma was treated with local radiotherapy and subsequently received growth hormone replacement therapy as an adult. Three years after starting growth hormone therapy, 23 years after her radiotherapy treatment, the patient's tumour recurred. Surveillance requirements for patients receiving growth hormone in this setting are discussed.en
dc.language.isoenen
dc.subjectCancer Recurrenceen
dc.subjectBrain Canceren
dc.subject.meshAdolescent-
dc.subject.meshAdult-
dc.subject.meshBrain Neoplasms-
dc.subject.meshFatal Outcome-
dc.subject.meshFemale-
dc.subject.meshGerminoma-
dc.subject.meshGrowth Hormone-
dc.subject.meshHumans-
dc.subject.meshHypopituitarism-
dc.subject.meshNeoplasm Recurrence, Local-
dc.subject.meshRadiotherapy, Adjuvant-
dc.subject.meshSella Turcica-
dc.titleRelapse of intracranial germinoma 23 years postirradiation in a patient given growth hormone replacement.en
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Oncology, Christie Hospital NHS Trust, Manchester, United Kingdom.en
dc.identifier.journalMedical and Pediatric Oncologyen

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