Screening by mammography, women with a family history of breast cancer.

2.50
Hdl Handle:
http://hdl.handle.net/10541/92019
Title:
Screening by mammography, women with a family history of breast cancer.
Authors:
Lalloo, Fiona; Boggis, C R; Evans, D Gareth R; Shenton, Andrew; Threlfall, Anthony G; Howell, Anthony ( 0000-0002-3879-5991 )
Abstract:
The aim of this study was to describe the experience of screening women under the age of 50 years with a family history of breast cancer. 1259 women attended the Family History Clinic in Manchester for their first and subsequent consultations between 30 September 1992 and 30 April 1997. All women were under the age of 50 years at the initial consultation and had a lifetime risk of breast cancer of 1 in 6 or greater. Seven prevalent, seven incident and two interval cancers were detected. The number of invasive cancers expected to occur if this high risk population had not been screened was 8.45 (in 2722 person years at risk). 12 invasive cancers were detected, giving a ratio of 1.42 (95% confidence interval 0.73-2.48). The overall cancer detection rates in this young, at risk population were similar to those in older women in the National Health Service Breast Screening Programme. The number of cancers detected in the study was greater than expected in this population. As the numbers were small, a national trial needs to be undertaken to confirm these results and to determine the long term effects of screening.
Citation:
Screening by mammography, women with a family history of breast cancer. 1998, 34 (6):937-40 Eur. J. Cancer
Journal:
European Journal of Cancer
Issue Date:
May-1998
URI:
http://hdl.handle.net/10541/92019
PubMed ID:
9797712
Type:
Article
Language:
en
ISSN:
0959-8049
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorLalloo, Fionaen
dc.contributor.authorBoggis, C Ren
dc.contributor.authorEvans, D Gareth Ren
dc.contributor.authorShenton, Andrewen
dc.contributor.authorThrelfall, Anthony Gen
dc.contributor.authorHowell, Anthonyen
dc.date.accessioned2010-02-12T15:15:07Z-
dc.date.available2010-02-12T15:15:07Z-
dc.date.issued1998-05-
dc.identifier.citationScreening by mammography, women with a family history of breast cancer. 1998, 34 (6):937-40 Eur. J. Canceren
dc.identifier.issn0959-8049-
dc.identifier.pmid9797712-
dc.identifier.urihttp://hdl.handle.net/10541/92019-
dc.description.abstractThe aim of this study was to describe the experience of screening women under the age of 50 years with a family history of breast cancer. 1259 women attended the Family History Clinic in Manchester for their first and subsequent consultations between 30 September 1992 and 30 April 1997. All women were under the age of 50 years at the initial consultation and had a lifetime risk of breast cancer of 1 in 6 or greater. Seven prevalent, seven incident and two interval cancers were detected. The number of invasive cancers expected to occur if this high risk population had not been screened was 8.45 (in 2722 person years at risk). 12 invasive cancers were detected, giving a ratio of 1.42 (95% confidence interval 0.73-2.48). The overall cancer detection rates in this young, at risk population were similar to those in older women in the National Health Service Breast Screening Programme. The number of cancers detected in the study was greater than expected in this population. As the numbers were small, a national trial needs to be undertaken to confirm these results and to determine the long term effects of screening.en
dc.language.isoenen
dc.subjectBreast Canceren
dc.subject.meshAdult-
dc.subject.meshBreast Neoplasms-
dc.subject.meshFemale-
dc.subject.meshFollow-Up Studies-
dc.subject.meshHumans-
dc.subject.meshMammography-
dc.subject.meshMass Screening-
dc.subject.meshMiddle Aged-
dc.subject.meshPedigree-
dc.subject.meshRisk Factors-
dc.subject.meshSensitivity and Specificity-
dc.titleScreening by mammography, women with a family history of breast cancer.en
dc.typeArticleen
dc.identifier.journalEuropean Journal of Canceren

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