2.50
Hdl Handle:
http://hdl.handle.net/10541/91970
Title:
Sources of error in bioimpedance spectroscopy.
Authors:
Bolton, M P; Ward, L C; Khan, A; Campbell, I; Nightingale, P; Dewit, O; Elia, M
Abstract:
Two different makes of bioimpedance spectrometer (UniQuest-SEAC SFB-3 and Xitron 4000B) were used for a series of measurements on volunteers and patients in intensive care. Although each machine was accurate over the frequency range 5 to 500 kHz when bench tested on model resistor-capacitor circuits, significant differences in their recorded impedance parameters appeared when used in vivo, especially on intensive care patients. A series of laboratory tests was performed on each machine simulating the situation in vivo to identify possible reasons for these differences. Whilst stray capacitance in the environment was identified as the major contributor to variability in high-frequency performance, interaction between electrode impedance and lead positioning was also a factor. The observed phase shift with frequency or time delay (Td) used in the Xitron modeling software appears to be the result of a time constant caused by stray capacitance and so is unlikely to have any biological meaning. Significant differences in the in vivo numerical values produced by bioimpedance spectrometers may be attributed to instrument design, data processing and, in particular, the clinical environment.
Affiliation:
Christie Hospital, Manchester, UK. bolton@fs1.with.man.ac.uk
Citation:
Sources of error in bioimpedance spectroscopy. 1998, 19 (2):235-45 Physiol Meas
Journal:
Physiological Measurement
Issue Date:
May-1998
URI:
http://hdl.handle.net/10541/91970
DOI:
10.1088/0967-3334/19/2/011
PubMed ID:
9626688
Type:
Article
Language:
en
ISSN:
0967-3334
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorBolton, M Pen
dc.contributor.authorWard, L Cen
dc.contributor.authorKhan, Aen
dc.contributor.authorCampbell, Ien
dc.contributor.authorNightingale, Pen
dc.contributor.authorDewit, Oen
dc.contributor.authorElia, Men
dc.date.accessioned2010-02-12T12:03:49Z-
dc.date.available2010-02-12T12:03:49Z-
dc.date.issued1998-05-
dc.identifier.citationSources of error in bioimpedance spectroscopy. 1998, 19 (2):235-45 Physiol Measen
dc.identifier.issn0967-3334-
dc.identifier.pmid9626688-
dc.identifier.doi10.1088/0967-3334/19/2/011-
dc.identifier.urihttp://hdl.handle.net/10541/91970-
dc.description.abstractTwo different makes of bioimpedance spectrometer (UniQuest-SEAC SFB-3 and Xitron 4000B) were used for a series of measurements on volunteers and patients in intensive care. Although each machine was accurate over the frequency range 5 to 500 kHz when bench tested on model resistor-capacitor circuits, significant differences in their recorded impedance parameters appeared when used in vivo, especially on intensive care patients. A series of laboratory tests was performed on each machine simulating the situation in vivo to identify possible reasons for these differences. Whilst stray capacitance in the environment was identified as the major contributor to variability in high-frequency performance, interaction between electrode impedance and lead positioning was also a factor. The observed phase shift with frequency or time delay (Td) used in the Xitron modeling software appears to be the result of a time constant caused by stray capacitance and so is unlikely to have any biological meaning. Significant differences in the in vivo numerical values produced by bioimpedance spectrometers may be attributed to instrument design, data processing and, in particular, the clinical environment.en
dc.language.isoenen
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshArtifacts-
dc.subject.meshBody Composition-
dc.subject.meshBody Water-
dc.subject.meshDiagnostic Errors-
dc.subject.meshEdema-
dc.subject.meshElectric Impedance-
dc.subject.meshElectrodes-
dc.subject.meshHumans-
dc.subject.meshIntensive Care-
dc.subject.meshMiddle Aged-
dc.subject.meshSoftware-
dc.titleSources of error in bioimpedance spectroscopy.en
dc.typeArticleen
dc.contributor.departmentChristie Hospital, Manchester, UK. bolton@fs1.with.man.ac.uken
dc.identifier.journalPhysiological Measurementen

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