2.50
Hdl Handle:
http://hdl.handle.net/10541/88625
Title:
Viral-encoded cyclins.
Authors:
Laman, Heike; Mann, David J; Jones, Nic
Abstract:
D-type cyclin homologs have been found in the genomes of herpesviruses associated with neoplasias. They appear to exploit features of G(1) cyclins but extend their properties to allow for deregulation of the cell cycle. Advances in the study of the molecular basis for these novel features as well as the potential role of viral cyclins in tumorigenesis are addressed.
Affiliation:
Molecular Oncology Laboratory, Imperial Cancer Research Fund, London, WC2A 3PX, UK.
Citation:
Viral-encoded cyclins. 2000, 10 (1):70-4 Curr. Opin. Genet. Dev.
Journal:
Current Opinion in Genetics & Development
Issue Date:
Feb-2000
URI:
http://hdl.handle.net/10541/88625
DOI:
10.1016/S0959-437X(99)00045-3
PubMed ID:
10679390
Type:
Article
Language:
en
ISSN:
0959-437X
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorLaman, Heikeen
dc.contributor.authorMann, David Jen
dc.contributor.authorJones, Nicen
dc.date.accessioned2009-12-29T11:14:00Z-
dc.date.available2009-12-29T11:14:00Z-
dc.date.issued2000-02-
dc.identifier.citationViral-encoded cyclins. 2000, 10 (1):70-4 Curr. Opin. Genet. Dev.en
dc.identifier.issn0959-437X-
dc.identifier.pmid10679390-
dc.identifier.doi10.1016/S0959-437X(99)00045-3-
dc.identifier.urihttp://hdl.handle.net/10541/88625-
dc.description.abstractD-type cyclin homologs have been found in the genomes of herpesviruses associated with neoplasias. They appear to exploit features of G(1) cyclins but extend their properties to allow for deregulation of the cell cycle. Advances in the study of the molecular basis for these novel features as well as the potential role of viral cyclins in tumorigenesis are addressed.en
dc.language.isoenen
dc.subjectCanceren
dc.subject.meshAnimals-
dc.subject.meshCell Cycle-
dc.subject.meshCyclin-Dependent Kinase Inhibitor p21-
dc.subject.meshCyclin-Dependent Kinases-
dc.subject.meshCyclins-
dc.subject.meshHerpesviridae-
dc.subject.meshHumans-
dc.subject.meshNeoplasms-
dc.subject.meshOncogenes-
dc.subject.meshViral Proteins-
dc.titleViral-encoded cyclins.en
dc.typeArticleen
dc.contributor.departmentMolecular Oncology Laboratory, Imperial Cancer Research Fund, London, WC2A 3PX, UK.en
dc.identifier.journalCurrent Opinion in Genetics & Developmenten

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