Customised compensation using intensity modulated beams delivered by dynamic multileaf collimation.

2.50
Hdl Handle:
http://hdl.handle.net/10541/87902
Title:
Customised compensation using intensity modulated beams delivered by dynamic multileaf collimation.
Authors:
Mott, Judith; Hounsell, Alan R; Budgell, Geoff J; Wilkinson, John M; Williams, Peter C
Abstract:
BACKGROUND AND PURPOSE: This paper describes the development of customised compensation by intensity modulated radiation therapy (IMRT), delivered by dynamic application of a multileaf collimator (MLC), in order to improve dose homogeneity in treatments of the pelvic region. The introduction of this simple IMRT procedure will help facilitate the clinical implementation of more complex 3D conformal therapy techniques. MATERIALS AND METHOD: Computer software is used to generate profiles of the intensity modulated beams which are required to deliver a uniform dose in a plane, passing through the isocentre and normal to the beam axis, under an irregular surface contour. These profiles are then operated on by interpreter software which determines the leaf trajectories that are necessary to deliver these beam profiles using a single, unidirectional sweep of the MLC leaves. A full dose calculation based on the calculated leaf positions is subsequently performed, allowing further fine adjustments to the modulation where required. RESULTS AND CONCLUSION: The compensation procedure has been successfully tested using films placed under a test phantom. The effect of the compensation procedure on dose distributions in the transverse plane has been investigated using an anthropomorphic phantom. Overall dose homogeneity has been improved through the use of customised compensation delivered by dynamic multileaf collimation.
Affiliation:
North Western Medical Physics, Christie Hospital NHS Trust, Withington, Manchester, UK.
Citation:
Customised compensation using intensity modulated beams delivered by dynamic multileaf collimation. 1999, 53 (1):59-65 Radiother Oncol
Journal:
Radiotherapy and Oncology
Issue Date:
Oct-1999
URI:
http://hdl.handle.net/10541/87902
DOI:
10.1016/S0167-8140(99)00125-5
PubMed ID:
10624855
Type:
Article
Language:
en
ISSN:
0167-8140
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMott, Judithen
dc.contributor.authorHounsell, Alan Ren
dc.contributor.authorBudgell, Geoff Jen
dc.contributor.authorWilkinson, John Men
dc.contributor.authorWilliams, Peter Cen
dc.date.accessioned2009-12-14T15:28:25Z-
dc.date.available2009-12-14T15:28:25Z-
dc.date.issued1999-10-
dc.identifier.citationCustomised compensation using intensity modulated beams delivered by dynamic multileaf collimation. 1999, 53 (1):59-65 Radiother Oncolen
dc.identifier.issn0167-8140-
dc.identifier.pmid10624855-
dc.identifier.doi10.1016/S0167-8140(99)00125-5-
dc.identifier.urihttp://hdl.handle.net/10541/87902-
dc.description.abstractBACKGROUND AND PURPOSE: This paper describes the development of customised compensation by intensity modulated radiation therapy (IMRT), delivered by dynamic application of a multileaf collimator (MLC), in order to improve dose homogeneity in treatments of the pelvic region. The introduction of this simple IMRT procedure will help facilitate the clinical implementation of more complex 3D conformal therapy techniques. MATERIALS AND METHOD: Computer software is used to generate profiles of the intensity modulated beams which are required to deliver a uniform dose in a plane, passing through the isocentre and normal to the beam axis, under an irregular surface contour. These profiles are then operated on by interpreter software which determines the leaf trajectories that are necessary to deliver these beam profiles using a single, unidirectional sweep of the MLC leaves. A full dose calculation based on the calculated leaf positions is subsequently performed, allowing further fine adjustments to the modulation where required. RESULTS AND CONCLUSION: The compensation procedure has been successfully tested using films placed under a test phantom. The effect of the compensation procedure on dose distributions in the transverse plane has been investigated using an anthropomorphic phantom. Overall dose homogeneity has been improved through the use of customised compensation delivered by dynamic multileaf collimation.en
dc.language.isoenen
dc.subject.meshHumans-
dc.subject.meshPelvis-
dc.subject.meshRadiotherapy Dosage-
dc.subject.meshRadiotherapy, Computer-Assisted-
dc.subject.meshSoftware-
dc.titleCustomised compensation using intensity modulated beams delivered by dynamic multileaf collimation.en
dc.typeArticleen
dc.contributor.departmentNorth Western Medical Physics, Christie Hospital NHS Trust, Withington, Manchester, UK.en
dc.identifier.journalRadiotherapy and Oncologyen

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