2.50
Hdl Handle:
http://hdl.handle.net/10541/87691
Title:
Epidemiology of bone tumours in children and young adults.
Authors:
Eyre, Rachel; Feltbower, Richard G; Mubwandarikwa, Emmanuel; Eden, Tim O B; McNally, Richard J Q
Abstract:
Although the epidemiology of malignant bone tumours in children and young adults has been explored, no definitive causation of any specific tumour has yet been identified. We performed a literature review (1970-2008) to find all papers covering possible aetiological factors involved in the development of bone tumours in children and young adults. Several associations have been reported with some consistency: the presence of hernias and Ewing sarcoma; high fluoride exposure and osteosarcoma; and parental farming and residence on a farm, younger age at puberty and family history of cancer for all bone tumours, especially osteosarcoma. Clearly further research is needed to confirm or refute these putative risk factors. It is likely that studies of gene-environment interactions may prove to be the most fruitful of future research.
Affiliation:
Institute of Health and Society, Newcastle University, Newcastle upon Tyne, England, United Kingdom.
Citation:
Epidemiology of bone tumours in children and young adults. 2009, 53 (6):941-52 Pediatr Blood Cancer
Journal:
Pediatric Blood & Cancer
Issue Date:
Dec-2009
URI:
http://hdl.handle.net/10541/87691
DOI:
10.1002/pbc.22194
PubMed ID:
19618453
Type:
Article
Language:
en
ISSN:
1545-5017
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorEyre, Rachelen
dc.contributor.authorFeltbower, Richard Gen
dc.contributor.authorMubwandarikwa, Emmanuelen
dc.contributor.authorEden, Tim O Ben
dc.contributor.authorMcNally, Richard J Qen
dc.date.accessioned2009-12-09T15:14:52Z-
dc.date.available2009-12-09T15:14:52Z-
dc.date.issued2009-12-
dc.identifier.citationEpidemiology of bone tumours in children and young adults. 2009, 53 (6):941-52 Pediatr Blood Canceren
dc.identifier.issn1545-5017-
dc.identifier.pmid19618453-
dc.identifier.doi10.1002/pbc.22194-
dc.identifier.urihttp://hdl.handle.net/10541/87691-
dc.description.abstractAlthough the epidemiology of malignant bone tumours in children and young adults has been explored, no definitive causation of any specific tumour has yet been identified. We performed a literature review (1970-2008) to find all papers covering possible aetiological factors involved in the development of bone tumours in children and young adults. Several associations have been reported with some consistency: the presence of hernias and Ewing sarcoma; high fluoride exposure and osteosarcoma; and parental farming and residence on a farm, younger age at puberty and family history of cancer for all bone tumours, especially osteosarcoma. Clearly further research is needed to confirm or refute these putative risk factors. It is likely that studies of gene-environment interactions may prove to be the most fruitful of future research.en
dc.language.isoenen
dc.subjectBone Canceren
dc.subject.meshBone Neoplasms-
dc.subject.meshChild-
dc.subject.meshHumans-
dc.subject.meshInsurance, Health-
dc.subject.meshSurvivors-
dc.subject.meshYoung Adult-
dc.titleEpidemiology of bone tumours in children and young adults.en
dc.typeArticleen
dc.contributor.departmentInstitute of Health and Society, Newcastle University, Newcastle upon Tyne, England, United Kingdom.en
dc.identifier.journalPediatric Blood & Canceren

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.