Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2).

2.50
Hdl Handle:
http://hdl.handle.net/10541/86667
Title:
Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2).
Authors:
Harris, Martin; Coyne, John; Tariq, M; Eyden, Brian P; Atkinson, M; Freemont, Anthony J; Varley, Jennifer; Attwooll, C; Telford, Nicholas
Abstract:
A case of extraskeletal myxoid chondrosarcoma (EMC) in which there was histochemical, immunohistochemical, and ultrastructural evidence of neuroendocrine differentiation is reported. Genetic investigations showed the recently described novel translocation t(9;17)(q22;q11.2) and associated fusion of the CHN and RBP56 genes, contrasting with the translocation t(9;22)(q22;q12) and EWS/CHN gene fusion found in the majority of EMCs.
Affiliation:
Department of Histopathology, Christie Hospital, Manchester, UK.
Citation:
Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2). 2000, 24 (7):1020-6 Am. J. Surg. Pathol.
Journal:
The American Journal of Surgical Pathology
Issue Date:
Jul-2000
URI:
http://hdl.handle.net/10541/86667
PubMed ID:
10895826
Type:
Article
Language:
en
ISSN:
0147-5185
Appears in Collections:
All Christie Publications ; All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorHarris, Martinen
dc.contributor.authorCoyne, Johnen
dc.contributor.authorTariq, Men
dc.contributor.authorEyden, Brian Pen
dc.contributor.authorAtkinson, Men
dc.contributor.authorFreemont, Anthony Jen
dc.contributor.authorVarley, Jenniferen
dc.contributor.authorAttwooll, Cen
dc.contributor.authorTelford, Nicholasen
dc.date.accessioned2009-11-23T11:56:33Z-
dc.date.available2009-11-23T11:56:33Z-
dc.date.issued2000-07-
dc.identifier.citationExtraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2). 2000, 24 (7):1020-6 Am. J. Surg. Pathol.en
dc.identifier.issn0147-5185-
dc.identifier.pmid10895826-
dc.identifier.urihttp://hdl.handle.net/10541/86667-
dc.description.abstractA case of extraskeletal myxoid chondrosarcoma (EMC) in which there was histochemical, immunohistochemical, and ultrastructural evidence of neuroendocrine differentiation is reported. Genetic investigations showed the recently described novel translocation t(9;17)(q22;q11.2) and associated fusion of the CHN and RBP56 genes, contrasting with the translocation t(9;22)(q22;q12) and EWS/CHN gene fusion found in the majority of EMCs.en
dc.language.isoenen
dc.subjectCancer DNAen
dc.subjectBiological Tumour Markersen
dc.subjectSoft Tissue Canceren
dc.subject.meshButtocks-
dc.subject.meshCell Differentiation-
dc.subject.meshChondrosarcoma-
dc.subject.meshChromosomes, Human, Pair 17-
dc.subject.meshChromosomes, Human, Pair 9-
dc.subject.meshCytogenetics-
dc.subject.meshHumans-
dc.subject.meshImmunohistochemistry-
dc.subject.meshIn Situ Hybridization-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNeurosecretory Systems-
dc.subject.meshProcollagen-
dc.subject.meshRNA, Messenger-
dc.subject.meshRNA, Neoplasm-
dc.subject.meshSilver Staining-
dc.subject.meshSoft Tissue Neoplasms-
dc.subject.meshTranslocation, Genetic-
dc.subject.meshTumor Markers, Biological-
dc.titleExtraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2).en
dc.typeArticleen
dc.contributor.departmentDepartment of Histopathology, Christie Hospital, Manchester, UK.en
dc.identifier.journalThe American Journal of Surgical Pathologyen

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