Treatment of endobronchial metastases with intraluminal radiotherapy.

2.50
Hdl Handle:
http://hdl.handle.net/10541/86640
Title:
Treatment of endobronchial metastases with intraluminal radiotherapy.
Authors:
Quantrill, S J; Burt, Paul A; Barber, Philip V; Stout, Ronald
Abstract:
Metastasis to the lung occurs quite commonly from certain types of extrapulmonary primary carcinoma. Spread to the bronchial lumen is relatively rare. When this does occur, symptoms resembling those of primary bronchial carcinoma are often present, in association with partial or complete obstruction of the bronchial lumen. Palliation of such symptoms is possible with the use of intraluminal radiotherapy (ILT). Between 1990 and 1998, 37 patients with endobronchial metastases were treated using this modality; a single fraction of radiation was delivered by the remote afterloading high dose rate microSelectron system. Data regarding these patients' characteristics and outcome are presented, following a retrospective review of case notes. The commonest symptoms were dyspnoea, cough and haemoptysis; the commonest primary tumour sites were breast, colorectum, oesophagus and kidney. Twenty-four (64.9%) patients had some improvement in symptoms following treatment. Mean overall survival was 280 days, range 9-1145 days. No serious adverse effects occurred. ILT is a relatively simple, safe and effective treatment in the palliation of symptoms due to endobronchial metastases.
Affiliation:
North West Lung Centre, Manchester, UK.
Citation:
Treatment of endobronchial metastases with intraluminal radiotherapy. 2000, 94 (4):369-72 Respir Med
Journal:
Respiratory Medicine
Issue Date:
Apr-2000
URI:
http://hdl.handle.net/10541/86640
DOI:
10.1053/rmed.1999.0731
PubMed ID:
10845436
Type:
Article
Language:
en
ISSN:
0954-6111
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorQuantrill, S Jen
dc.contributor.authorBurt, Paul Aen
dc.contributor.authorBarber, Philip Ven
dc.contributor.authorStout, Ronalden
dc.date.accessioned2009-11-23T09:59:15Z-
dc.date.available2009-11-23T09:59:15Z-
dc.date.issued2000-04-
dc.identifier.citationTreatment of endobronchial metastases with intraluminal radiotherapy. 2000, 94 (4):369-72 Respir Meden
dc.identifier.issn0954-6111-
dc.identifier.pmid10845436-
dc.identifier.doi10.1053/rmed.1999.0731-
dc.identifier.urihttp://hdl.handle.net/10541/86640-
dc.description.abstractMetastasis to the lung occurs quite commonly from certain types of extrapulmonary primary carcinoma. Spread to the bronchial lumen is relatively rare. When this does occur, symptoms resembling those of primary bronchial carcinoma are often present, in association with partial or complete obstruction of the bronchial lumen. Palliation of such symptoms is possible with the use of intraluminal radiotherapy (ILT). Between 1990 and 1998, 37 patients with endobronchial metastases were treated using this modality; a single fraction of radiation was delivered by the remote afterloading high dose rate microSelectron system. Data regarding these patients' characteristics and outcome are presented, following a retrospective review of case notes. The commonest symptoms were dyspnoea, cough and haemoptysis; the commonest primary tumour sites were breast, colorectum, oesophagus and kidney. Twenty-four (64.9%) patients had some improvement in symptoms following treatment. Mean overall survival was 280 days, range 9-1145 days. No serious adverse effects occurred. ILT is a relatively simple, safe and effective treatment in the palliation of symptoms due to endobronchial metastases.en
dc.language.isoenen
dc.subjectBronchial Canceren
dc.subjectHaemoptysisen
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshBrachytherapy-
dc.subject.meshBronchial Neoplasms-
dc.subject.meshDose-Response Relationship, Radiation-
dc.subject.meshFemale-
dc.subject.meshHemoptysis-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshPalliative Care-
dc.subject.meshRetrospective Studies-
dc.subject.meshSurvival Analysis-
dc.subject.meshTreatment Outcome-
dc.titleTreatment of endobronchial metastases with intraluminal radiotherapy.en
dc.typeArticleen
dc.contributor.departmentNorth West Lung Centre, Manchester, UK.en
dc.identifier.journalRespiratory Medicineen
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