Myofibroblast transformation in metastatic extramedullary chronic myeloid leukemia: a case report.

2.50
Hdl Handle:
http://hdl.handle.net/10541/85165
Title:
Myofibroblast transformation in metastatic extramedullary chronic myeloid leukemia: a case report.
Authors:
Ru, Yong-Xin; Eyden, Brian P; Li, Qing-Hua; Mao, Bing-Yu; Liu, En-Bin; Pang, Tian-Xiang
Abstract:
Primary and metastatic carcinomas have a reactive stroma characterized by many myofibroblasts. These cells have also been documented in nonepithelial malignancies, such as sarcomas, malignant melanoma, and lymphoid tumors but in generally far fewer numbers. In non-Hodgkin's lymphoma, Hodgkin's disease, and leukemia, myofibroblasts are rather rarely documented. In particular, there appear to be no reports of myofibroblasts in either primary bone-marrow/peripheral blood leukemia or secondary deposits of leukemia. In this paper, a case of a relapsed chronic myeloid leukemia appearing in an inguinal lymph node is described, containing many myofibroblasts. The case is detailed and presented with a discussion on the role of myofibroblasts in the progression of nonepithelial cancers.
Affiliation:
Institute of Hematology & Blood Diseases Hospital, Peking Union Medical College, Tianjin, China.
Citation:
Myofibroblast transformation in metastatic extramedullary chronic myeloid leukemia: a case report. 2009, 33 (3):136-40 Ultrastruct Pathol
Journal:
Ultrastructural Pathology
Issue Date:
2009
URI:
http://hdl.handle.net/10541/85165
DOI:
10.1080/01913120902786961
PubMed ID:
19479654
Type:
Article
Language:
en
ISSN:
1521-0758
Appears in Collections:
All Christie Publications ; Radiology

Full metadata record

DC FieldValue Language
dc.contributor.authorRu, Yong-Xinen
dc.contributor.authorEyden, Brian Pen
dc.contributor.authorLi, Qing-Huaen
dc.contributor.authorMao, Bing-Yuen
dc.contributor.authorLiu, En-Binen
dc.contributor.authorPang, Tian-Xiangen
dc.date.accessioned2009-11-02T13:18:05Z-
dc.date.available2009-11-02T13:18:05Z-
dc.date.issued2009-
dc.identifier.citationMyofibroblast transformation in metastatic extramedullary chronic myeloid leukemia: a case report. 2009, 33 (3):136-40 Ultrastruct Patholen
dc.identifier.issn1521-0758-
dc.identifier.pmid19479654-
dc.identifier.doi10.1080/01913120902786961-
dc.identifier.urihttp://hdl.handle.net/10541/85165-
dc.description.abstractPrimary and metastatic carcinomas have a reactive stroma characterized by many myofibroblasts. These cells have also been documented in nonepithelial malignancies, such as sarcomas, malignant melanoma, and lymphoid tumors but in generally far fewer numbers. In non-Hodgkin's lymphoma, Hodgkin's disease, and leukemia, myofibroblasts are rather rarely documented. In particular, there appear to be no reports of myofibroblasts in either primary bone-marrow/peripheral blood leukemia or secondary deposits of leukemia. In this paper, a case of a relapsed chronic myeloid leukemia appearing in an inguinal lymph node is described, containing many myofibroblasts. The case is detailed and presented with a discussion on the role of myofibroblasts in the progression of nonepithelial cancers.en
dc.language.isoenen
dc.subjectCancerous Cell Transformationen
dc.subjectMyelogenic Leukaemiaen
dc.subject.meshCell Transformation, Neoplastic-
dc.subject.meshDisease Progression-
dc.subject.meshFemale-
dc.subject.meshFibroblasts-
dc.subject.meshHumans-
dc.subject.meshLeukemia, Myelogenous, Chronic, BCR-ABL Positive-
dc.subject.meshLymph Nodes-
dc.subject.meshMicroscopy, Electron, Transmission-
dc.subject.meshMiddle Aged-
dc.subject.meshMyocytes, Smooth Muscle-
dc.subject.meshOrganelles-
dc.subject.meshRecurrence-
dc.titleMyofibroblast transformation in metastatic extramedullary chronic myeloid leukemia: a case report.en
dc.typeArticleen
dc.contributor.departmentInstitute of Hematology & Blood Diseases Hospital, Peking Union Medical College, Tianjin, China.en
dc.identifier.journalUltrastructural Pathologyen
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