2.50
Hdl Handle:
http://hdl.handle.net/10541/84061
Title:
Somatic glypican 3 (GPC3) mutations in Wilms' tumour.
Authors:
White, Gavin R M; Kelsey, Anna M; Varley, Jennifer; Birch, Jillian M
Abstract:
Tumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development.
Affiliation:
Cancer Research UK Cancer Genetics Group, Paterson Institute for Cancer Research, Wilmslow Road, Manchester M20 4BX, UK.
Citation:
Somatic glypican 3 (GPC3) mutations in Wilms' tumour. 2002, 86 (12):1920-2 Br. J. Cancer
Journal:
British Journal of Cancer
Issue Date:
17-Jun-2002
URI:
http://hdl.handle.net/10541/84061
DOI:
10.1038/sj.bjc.6600417
PubMed ID:
12085187
Type:
Article
Language:
en
ISSN:
0007-0920
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorWhite, Gavin R Men
dc.contributor.authorKelsey, Anna Men
dc.contributor.authorVarley, Jenniferen
dc.contributor.authorBirch, Jillian Men
dc.date.accessioned2009-10-12T12:27:24Z-
dc.date.available2009-10-12T12:27:24Z-
dc.date.issued2002-06-17-
dc.identifier.citationSomatic glypican 3 (GPC3) mutations in Wilms' tumour. 2002, 86 (12):1920-2 Br. J. Canceren
dc.identifier.issn0007-0920-
dc.identifier.pmid12085187-
dc.identifier.doi10.1038/sj.bjc.6600417-
dc.identifier.urihttp://hdl.handle.net/10541/84061-
dc.description.abstractTumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development.en
dc.language.isoenen
dc.subjectKidney Canceren
dc.subjectRenal Canceren
dc.subjectWilms Tumouren
dc.subject.meshDNA Primers-
dc.subject.meshGlypicans-
dc.subject.meshHeparan Sulfate Proteoglycans-
dc.subject.meshHumans-
dc.subject.meshKidney Neoplasms-
dc.subject.meshMale-
dc.subject.meshMutation-
dc.subject.meshPolymerase Chain Reaction-
dc.subject.meshPolymorphism, Single-Stranded Conformational-
dc.subject.meshWilms Tumor-
dc.titleSomatic glypican 3 (GPC3) mutations in Wilms' tumour.en
dc.typeArticleen
dc.contributor.departmentCancer Research UK Cancer Genetics Group, Paterson Institute for Cancer Research, Wilmslow Road, Manchester M20 4BX, UK.en
dc.identifier.journalBritish Journal of Canceren

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