Clinical implementation of dynamic multileaf collimation for compensated bladder treatments.

2.50
Hdl Handle:
http://hdl.handle.net/10541/83354
Title:
Clinical implementation of dynamic multileaf collimation for compensated bladder treatments.
Authors:
Budgell, Geoff J; Mott, Judith; Logue, John P; Hounsell, Alan R
Abstract:
BACKGROUND AND PURPOSE: To describe the clinical implementation of dynamic multileaf collimation (DMLC). Custom compensated four-field treatments of carcinoma of the bladder have been used as a simple test site for the introduction of intensity modulated radiotherapy.MATERIALS AND METHODS: Compensating intensity modulations are calculated from computed tomography (CT) data, accounting for scattered, as well as primary radiation. Modulations are converted to multileaf collimator (MLC) leaf and jaw settings for dynamic delivery on a linear accelerator. A full dose calculation is carried out, accounting for dynamic leaf and jaw motion and transmission through these components. Before treatment, a test run of the delivery is performed and an absolute dose measurement made in a water or solid water phantom. Treatments are verified by in vivo diode measurements and real-time electronic portal imaging. RESULTS: Seven patients have been treated using DMLC. The technique improves dose homogeneity within the target volume, reducing high dose areas and compensating for loss of scatter at the beam edge. A typical total treatment time is 20 min. CONCLUSIONS: Compensated bladder treatments have proven an effective test site for DMLC in an extremely busy clinic.
Affiliation:
North Western Medical Physics, Christie Hospital NHS Trust, Wilmslow Road, Withington, M20 4BX, Manchester, UK.
Citation:
Clinical implementation of dynamic multileaf collimation for compensated bladder treatments. 2001, 59 (1):31-8 Radiother Oncol
Journal:
Radiotherapy and Oncology
Issue Date:
Apr-2001
URI:
http://hdl.handle.net/10541/83354
PubMed ID:
11295203
Type:
Article
Language:
en
ISSN:
0167-8140
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorBudgell, Geoff J-
dc.contributor.authorMott, Judith-
dc.contributor.authorLogue, John P-
dc.contributor.authorHounsell, Alan R-
dc.date.accessioned2009-10-02T12:21:12Z-
dc.date.available2009-10-02T12:21:12Z-
dc.date.issued2001-04-
dc.identifier.citationClinical implementation of dynamic multileaf collimation for compensated bladder treatments. 2001, 59 (1):31-8 Radiother Oncolen
dc.identifier.issn0167-8140-
dc.identifier.pmid11295203-
dc.identifier.urihttp://hdl.handle.net/10541/83354-
dc.description.abstractBACKGROUND AND PURPOSE: To describe the clinical implementation of dynamic multileaf collimation (DMLC). Custom compensated four-field treatments of carcinoma of the bladder have been used as a simple test site for the introduction of intensity modulated radiotherapy.MATERIALS AND METHODS: Compensating intensity modulations are calculated from computed tomography (CT) data, accounting for scattered, as well as primary radiation. Modulations are converted to multileaf collimator (MLC) leaf and jaw settings for dynamic delivery on a linear accelerator. A full dose calculation is carried out, accounting for dynamic leaf and jaw motion and transmission through these components. Before treatment, a test run of the delivery is performed and an absolute dose measurement made in a water or solid water phantom. Treatments are verified by in vivo diode measurements and real-time electronic portal imaging. RESULTS: Seven patients have been treated using DMLC. The technique improves dose homogeneity within the target volume, reducing high dose areas and compensating for loss of scatter at the beam edge. A typical total treatment time is 20 min. CONCLUSIONS: Compensated bladder treatments have proven an effective test site for DMLC in an extremely busy clinic.en
dc.language.isoenen
dc.subjectUrinary Bladder Canceren
dc.subject.meshCarcinoma-
dc.subject.meshDose-Response Relationship, Radiation-
dc.subject.meshPhantoms, Imaging-
dc.subject.meshPrognosis-
dc.subject.meshRadiation Dosage-
dc.subject.meshRadiation Injuries-
dc.subject.meshRadiotherapy Planning, Computer-Assisted-
dc.subject.meshRadiotherapy, High-Energy-
dc.subject.meshSampling Studies-
dc.subject.meshSensitivity and Specificity-
dc.subject.meshTreatment Outcome-
dc.subject.meshUrinary Bladder Neoplasms-
dc.titleClinical implementation of dynamic multileaf collimation for compensated bladder treatments.en
dc.typeArticleen
dc.contributor.departmentNorth Western Medical Physics, Christie Hospital NHS Trust, Wilmslow Road, Withington, M20 4BX, Manchester, UK.en
dc.identifier.journalRadiotherapy and Oncologyen

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