Evidence of nerve sheath differentiation and high grade morphology in sclerosing epithelioid fibrosarcoma.

2.50
Hdl Handle:
http://hdl.handle.net/10541/82507
Title:
Evidence of nerve sheath differentiation and high grade morphology in sclerosing epithelioid fibrosarcoma.
Authors:
Hanson, I M; Pearson, J M; Eyden, Brian P; Slawik, S; Harris, Martin
Abstract:
Sclerosing epithelioid fibrosarcoma is a recently described sarcoma in which ultrastructural evidence of fibroblastic differentiation forms part of the diagnostic criteria. This report describes a further case of this tumour, which showed evidence of both fibroblastic and perineurial differentiation by immunohistochemistry and electron microscopy, and which had areas of high grade morphology. The tumour metastasised and the patient died of disease 12 months after presentation. The relevance of these findings to diagnosis and differentiation in these tumours is discussed.
Affiliation:
Department of Histopathology, Royal Bolton Hospital, Minerva Road, Farnworth, Bolton BL4 0JR, UK. isabelle.hanson@boltonh-tr.nwest.nhs.uk
Citation:
Evidence of nerve sheath differentiation and high grade morphology in sclerosing epithelioid fibrosarcoma. 2001, 54 (9):721-3 J. Clin. Pathol.
Journal:
Journal of Clinical Pathology
Issue Date:
Sep-2001
URI:
http://hdl.handle.net/10541/82507
PubMed ID:
11533083
Type:
Article
Language:
en
ISSN:
0021-9746
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorHanson, I M-
dc.contributor.authorPearson, J M-
dc.contributor.authorEyden, Brian P-
dc.contributor.authorSlawik, S-
dc.contributor.authorHarris, Martin-
dc.date.accessioned2009-09-24T12:06:39Z-
dc.date.available2009-09-24T12:06:39Z-
dc.date.issued2001-09-
dc.identifier.citationEvidence of nerve sheath differentiation and high grade morphology in sclerosing epithelioid fibrosarcoma. 2001, 54 (9):721-3 J. Clin. Pathol.en
dc.identifier.issn0021-9746-
dc.identifier.pmid11533083-
dc.identifier.urihttp://hdl.handle.net/10541/82507-
dc.description.abstractSclerosing epithelioid fibrosarcoma is a recently described sarcoma in which ultrastructural evidence of fibroblastic differentiation forms part of the diagnostic criteria. This report describes a further case of this tumour, which showed evidence of both fibroblastic and perineurial differentiation by immunohistochemistry and electron microscopy, and which had areas of high grade morphology. The tumour metastasised and the patient died of disease 12 months after presentation. The relevance of these findings to diagnosis and differentiation in these tumours is discussed.en
dc.language.isoenen
dc.subjectRetroperitoneal Canceren
dc.subjectSpinal Canceren
dc.subject.meshCell Differentiation-
dc.subject.meshFatal Outcome-
dc.subject.meshFibrosarcoma-
dc.subject.meshFollow-Up Studies-
dc.subject.meshHumans-
dc.subject.meshLumbar Vertebrae-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshRetroperitoneal Neoplasms-
dc.subject.meshSpinal Neoplasms-
dc.titleEvidence of nerve sheath differentiation and high grade morphology in sclerosing epithelioid fibrosarcoma.en
dc.typeArticleen
dc.contributor.departmentDepartment of Histopathology, Royal Bolton Hospital, Minerva Road, Farnworth, Bolton BL4 0JR, UK. isabelle.hanson@boltonh-tr.nwest.nhs.uken
dc.identifier.journalJournal of Clinical Pathologyen

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