Total registration of non-Hodgkin's lymphoma and Hodgkin's disease in Scotland: effect of deprivation and caseload on outcome.

2.50
Hdl Handle:
http://hdl.handle.net/10541/78953
Title:
Total registration of non-Hodgkin's lymphoma and Hodgkin's disease in Scotland: effect of deprivation and caseload on outcome.
Authors:
Ewing, Joanne; White, J M; Rattray, A; Lessells, A; Mackie, M J
Abstract:
All cases S16 years of age with a histological diagnosis of non-Hodgkin's lymphoma (NHL) and Hodgkin's disease (HD) presented in Scotland between 1 January 1994 and 31 December 1996 were registered prospectively in the Scotland and Newcastle Lymphoma Group database by a process of total registration. The census population of Scotland in 1996-1997 was 5.1 million. One thousand seven hundred and sixty three patients were registered with NHL and 350 patients with HD. These patients have been followed up for a median of 47 months in the case of NHL and 51 months for HD cases. Actuarial 5-year survival for adult NHL was 35% and for HD, 75%. Outcome for both NHL and HD was particularly poor in the population over 60 years with median survival of 18 months for NHL and 27 months for HD. When analysis of survival was related to degree of material deprivation using the Carstairs score a significantly poorer survival was seen for NHL with increasing deprivation that could not be explained by a different pattern of age or stage at presentation. Deprivation had no impact on incidence or survival in HD. Analysis of impact of caseload of the physician initiating therapy showed no significant difference in 5-year survival.
Affiliation:
Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road MBX 20 4, Manchester, UK.
Citation:
Total registration of non-Hodgkin's lymphoma and Hodgkin's disease in Scotland: effect of deprivation and caseload on outcome. 2003, 8 (4):211-20 Hematology
Journal:
Hematology
Issue Date:
Aug-2003
URI:
http://hdl.handle.net/10541/78953
DOI:
10.1080/1024533031000135685
PubMed ID:
12911938
Type:
Article
Language:
en
ISSN:
1024-5332
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorEwing, Joanne-
dc.contributor.authorWhite, J M-
dc.contributor.authorRattray, A-
dc.contributor.authorLessells, A-
dc.contributor.authorMackie, M J-
dc.date.accessioned2009-08-27T15:01:58Z-
dc.date.available2009-08-27T15:01:58Z-
dc.date.issued2003-08-
dc.identifier.citationTotal registration of non-Hodgkin's lymphoma and Hodgkin's disease in Scotland: effect of deprivation and caseload on outcome. 2003, 8 (4):211-20 Hematologyen
dc.identifier.issn1024-5332-
dc.identifier.pmid12911938-
dc.identifier.doi10.1080/1024533031000135685-
dc.identifier.urihttp://hdl.handle.net/10541/78953-
dc.description.abstractAll cases S16 years of age with a histological diagnosis of non-Hodgkin's lymphoma (NHL) and Hodgkin's disease (HD) presented in Scotland between 1 January 1994 and 31 December 1996 were registered prospectively in the Scotland and Newcastle Lymphoma Group database by a process of total registration. The census population of Scotland in 1996-1997 was 5.1 million. One thousand seven hundred and sixty three patients were registered with NHL and 350 patients with HD. These patients have been followed up for a median of 47 months in the case of NHL and 51 months for HD cases. Actuarial 5-year survival for adult NHL was 35% and for HD, 75%. Outcome for both NHL and HD was particularly poor in the population over 60 years with median survival of 18 months for NHL and 27 months for HD. When analysis of survival was related to degree of material deprivation using the Carstairs score a significantly poorer survival was seen for NHL with increasing deprivation that could not be explained by a different pattern of age or stage at presentation. Deprivation had no impact on incidence or survival in HD. Analysis of impact of caseload of the physician initiating therapy showed no significant difference in 5-year survival.en
dc.language.isoenen
dc.subject.meshAdolescent-
dc.subject.meshAdult-
dc.subject.meshAge Factors-
dc.subject.meshAged-
dc.subject.meshFemale-
dc.subject.meshFollow-Up Studies-
dc.subject.meshHodgkin Disease-
dc.subject.meshHumans-
dc.subject.meshIncidence-
dc.subject.meshLymphoma, Non-Hodgkin-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshPoverty-
dc.subject.meshProspective Studies-
dc.subject.meshRegistries-
dc.subject.meshScotland-
dc.subject.meshSex Factors-
dc.subject.meshSurvival Analysis-
dc.subject.meshTreatment Outcome-
dc.subject.meshWorkload-
dc.titleTotal registration of non-Hodgkin's lymphoma and Hodgkin's disease in Scotland: effect of deprivation and caseload on outcome.en
dc.typeArticleen
dc.contributor.departmentPaterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road MBX 20 4, Manchester, UK.en
dc.identifier.journalHematologyen

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