2.50
Hdl Handle:
http://hdl.handle.net/10541/78376
Title:
Cdc14 phosphatase resolves the rDNA segregation delay.
Authors:
Pereira, Gislene; Schiebel, Elmar
Abstract:
Sister chromatid segregation in anaphase of mitosis is initiated through cleavage of cohesin by the protease separase. Two studies now show that this view is valid for most chromosomal DNA, but not for the highly repetitive ribosomal DNA (rDNA) and telomeres. The disjunction of these regions of the chromosome occurs in mid-anaphase, long after cohesin cleavage, and is regulated by the conserved phosphatase Cdc14.
Citation:
Cdc14 phosphatase resolves the rDNA segregation delay. 2004, 6 (6):473-5 Nat. Cell Biol.
Journal:
Nature Cell Biology
Issue Date:
Jun-2004
URI:
http://hdl.handle.net/10541/78376
DOI:
10.1038/ncb0604-473
PubMed ID:
15170454
Type:
Article
Language:
en
ISSN:
1465-7392
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorPereira, Gislene-
dc.contributor.authorSchiebel, Elmar-
dc.date.accessioned2009-08-24T14:12:38Z-
dc.date.available2009-08-24T14:12:38Z-
dc.date.issued2004-06-
dc.identifier.citationCdc14 phosphatase resolves the rDNA segregation delay. 2004, 6 (6):473-5 Nat. Cell Biol.en
dc.identifier.issn1465-7392-
dc.identifier.pmid15170454-
dc.identifier.doi10.1038/ncb0604-473-
dc.identifier.urihttp://hdl.handle.net/10541/78376-
dc.description.abstractSister chromatid segregation in anaphase of mitosis is initiated through cleavage of cohesin by the protease separase. Two studies now show that this view is valid for most chromosomal DNA, but not for the highly repetitive ribosomal DNA (rDNA) and telomeres. The disjunction of these regions of the chromosome occurs in mid-anaphase, long after cohesin cleavage, and is regulated by the conserved phosphatase Cdc14.en
dc.language.isoenen
dc.subject.meshAnaphase-
dc.subject.meshCell Cycle Proteins-
dc.subject.meshChromosome Segregation-
dc.subject.meshDNA, Ribosomal-
dc.subject.meshMitosis-
dc.subject.meshProtein Tyrosine Phosphatases-
dc.subject.meshSaccharomyces cerevisiae-
dc.subject.meshSaccharomyces cerevisiae Proteins-
dc.subject.meshTelomere-
dc.titleCdc14 phosphatase resolves the rDNA segregation delay.en
dc.typeArticleen
dc.identifier.journalNature Cell Biologyen

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