2.50
Hdl Handle:
http://hdl.handle.net/10541/78223
Title:
Radiotherapy for head and neck cancer in elderly patients.
Authors:
Schofield, Clare P; Sykes, Andrew J; Slevin, Nicholas J ( 0000-0002-3367-7013 ) ; Rashid, Noor Z Z
Abstract:
BACKGROUND AND PURPOSE: Elderly patients with head and neck cancer may not be treated aggressively with radiotherapy, due to concerns regarding tolerance of treatment and toxicity. A retrospective study was undertaken of patients aged 80 years and over, treated by definitive radiotherapy for head and neck cancer. MATERIAL AND METHODS: 98 patients aged 80-92 received radiotherapy for carcinoma of the head and neck between 1991 and 1995. All patients received beam directed radiotherapy with radical intent using an immobilisation shell. RESULTS: Cancer specific survival was 59% and overall local control was 70% at 5 years. Both were significantly affected by T stage and site of disease. Cancer specific survival was comparable to that of patients aged below 80 years. Seven patients died within 6 months of the treatment. Three patients developed severe late toxicity. Metastatic disease occurred in eight patients. CONCLUSIONS: Radiotherapy is a beneficial and well tolerated treatment in elderly patients with carcinoma of the head and neck.
Affiliation:
Department of Clinical Oncology, Christie Hospital, Oak Road, Withington, Manchester, UK.
Citation:
Radiotherapy for head and neck cancer in elderly patients. 2003, 69 (1):37-42 Radiother Oncol
Journal:
Radiotherapy and Oncology
Issue Date:
Oct-2003
URI:
http://hdl.handle.net/10541/78223
PubMed ID:
14597355
Type:
Article
Language:
en
ISSN:
0167-8140
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorSchofield, Clare P-
dc.contributor.authorSykes, Andrew J-
dc.contributor.authorSlevin, Nicholas J-
dc.contributor.authorRashid, Noor Z Z-
dc.date.accessioned2009-08-21T14:26:45Z-
dc.date.available2009-08-21T14:26:45Z-
dc.date.issued2003-10-
dc.identifier.citationRadiotherapy for head and neck cancer in elderly patients. 2003, 69 (1):37-42 Radiother Oncolen
dc.identifier.issn0167-8140-
dc.identifier.pmid14597355-
dc.identifier.urihttp://hdl.handle.net/10541/78223-
dc.description.abstractBACKGROUND AND PURPOSE: Elderly patients with head and neck cancer may not be treated aggressively with radiotherapy, due to concerns regarding tolerance of treatment and toxicity. A retrospective study was undertaken of patients aged 80 years and over, treated by definitive radiotherapy for head and neck cancer. MATERIAL AND METHODS: 98 patients aged 80-92 received radiotherapy for carcinoma of the head and neck between 1991 and 1995. All patients received beam directed radiotherapy with radical intent using an immobilisation shell. RESULTS: Cancer specific survival was 59% and overall local control was 70% at 5 years. Both were significantly affected by T stage and site of disease. Cancer specific survival was comparable to that of patients aged below 80 years. Seven patients died within 6 months of the treatment. Three patients developed severe late toxicity. Metastatic disease occurred in eight patients. CONCLUSIONS: Radiotherapy is a beneficial and well tolerated treatment in elderly patients with carcinoma of the head and neck.en
dc.language.isoenen
dc.subjectMouth Canceren
dc.subjectOtorhinolaryngologic Canceren
dc.subjectCancer Recurrenceen
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshCarcinoma, Squamous Cell-
dc.subject.meshDose Fractionation-
dc.subject.meshHumans-
dc.subject.meshLymphatic Metastasis-
dc.subject.meshMouth Neoplasms-
dc.subject.meshNeoplasm Recurrence, Local-
dc.subject.meshOtorhinolaryngologic Neoplasms-
dc.subject.meshRadiation Injuries-
dc.subject.meshRadiotherapy Dosage-
dc.subject.meshRetrospective Studies-
dc.subject.meshSurvival Rate-
dc.titleRadiotherapy for head and neck cancer in elderly patients.en
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Oncology, Christie Hospital, Oak Road, Withington, Manchester, UK.en
dc.identifier.journalRadiotherapy and Oncologyen

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