Radical radiotherapy for early laryngeal cancer in a patient with human immunodeficiency virus: no evidence of increased toxicity.

2.50
Hdl Handle:
http://hdl.handle.net/10541/78103
Title:
Radical radiotherapy for early laryngeal cancer in a patient with human immunodeficiency virus: no evidence of increased toxicity.
Authors:
Harris, Maggie A; Wise, M S; Bonington, A; Slevin, Nicholas J ( 0000-0002-3367-7013 )
Abstract:
There are very few reported cases of laryngeal squamous cell carcinoma (SCC) in patients with a background of human immunodeficiency virus (HIV) infection. We report a case of a 42-year-old man who developed a T2 N0 left vocal cord well differentiated SCC with an 11 year history of HIV infection. He successfully completed a course of radical radiotherapy 66 Gy in 33 fractions over 47 days. During his treatment he experienced only a grade 1 Radiation Therapy Oncology Group (RTOG) acute toxicity reaction to the larynx and no weight loss. At 32 months follow up he remains disease free and has no significant late morbidity. Prior to his radiotherapy his CD4 count was 350 cells mm(-3); we discuss the view that the treatment chosen needs to be individually tailored with respect to the patient's immune status.
Affiliation:
Department of Clinical Oncology, Christie Hospital NHS Trust, Wilmslow Road, Withington, Manchester M20 4BX, UK.
Citation:
Radical radiotherapy for early laryngeal cancer in a patient with human immunodeficiency virus: no evidence of increased toxicity. 2004, 77 (918):519-20 Br J Radiol
Journal:
The British Journal of Radiology
Issue Date:
Jun-2004
URI:
http://hdl.handle.net/10541/78103
DOI:
10.1259/bjr/51408454
PubMed ID:
15151976
Type:
Article
Language:
en
ISSN:
0007-1285
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorHarris, Maggie A-
dc.contributor.authorWise, M S-
dc.contributor.authorBonington, A-
dc.contributor.authorSlevin, Nicholas J-
dc.date.accessioned2009-08-21T09:27:48Z-
dc.date.available2009-08-21T09:27:48Z-
dc.date.issued2004-06-
dc.identifier.citationRadical radiotherapy for early laryngeal cancer in a patient with human immunodeficiency virus: no evidence of increased toxicity. 2004, 77 (918):519-20 Br J Radiolen
dc.identifier.issn0007-1285-
dc.identifier.pmid15151976-
dc.identifier.doi10.1259/bjr/51408454-
dc.identifier.urihttp://hdl.handle.net/10541/78103-
dc.description.abstractThere are very few reported cases of laryngeal squamous cell carcinoma (SCC) in patients with a background of human immunodeficiency virus (HIV) infection. We report a case of a 42-year-old man who developed a T2 N0 left vocal cord well differentiated SCC with an 11 year history of HIV infection. He successfully completed a course of radical radiotherapy 66 Gy in 33 fractions over 47 days. During his treatment he experienced only a grade 1 Radiation Therapy Oncology Group (RTOG) acute toxicity reaction to the larynx and no weight loss. At 32 months follow up he remains disease free and has no significant late morbidity. Prior to his radiotherapy his CD4 count was 350 cells mm(-3); we discuss the view that the treatment chosen needs to be individually tailored with respect to the patient's immune status.en
dc.language.isoenen
dc.subjectLaryngeal Canceren
dc.subject.meshAdult-
dc.subject.meshCarcinoma, Squamous Cell-
dc.subject.meshErythema-
dc.subject.meshHIV Infections-
dc.subject.meshHumans-
dc.subject.meshLaryngeal Neoplasms-
dc.subject.meshMale-
dc.subject.meshRadiation Injuries-
dc.subject.meshSkin-
dc.subject.meshVocal Cords-
dc.titleRadical radiotherapy for early laryngeal cancer in a patient with human immunodeficiency virus: no evidence of increased toxicity.en
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Oncology, Christie Hospital NHS Trust, Wilmslow Road, Withington, Manchester M20 4BX, UK.en
dc.identifier.journalThe British Journal of Radiologyen

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