An assessment of clinically optimal gold marker length and diameter for pelvic radiotherapy verification using an amorphous silicon flat panel electronic portal imaging device.

2.50
Hdl Handle:
http://hdl.handle.net/10541/76474
Title:
An assessment of clinically optimal gold marker length and diameter for pelvic radiotherapy verification using an amorphous silicon flat panel electronic portal imaging device.
Authors:
Henry, Ann M; Stratford, Julia; Davies, Julie; McCarthy, Claire; Swindell, Ric; Sykes, Jonathan R; Moore, Christopher J; Price, Patricia M; Khoo, Vincent S
Abstract:
Verification of target organ position is essential for the accurate delivery of conformal radiotherapy. Megavoltage electronic portal imaging with flat panel amorphous silicon detectors delivers high quality images that can be used for verification of bony landmark position. Gold markers implanted into the target organ can be visualized and used as a surrogate of actual organ position. On-line compensation for marker displacement, by adjusting patient position, can reduce geometric errors associated with radiation delivery. This study assesses the optimal marker length and diameter to be used with an amorphous silicon (a-Si) flat panel detector and electronic portal images (EPIs), prior to implementation of a clinical programme of gold marker insertion in prostate cancer patients. Seven marker sizes varying from 3 mm to 8 mm in length and 0.8 mm to 1.1 mm in diameter were investigated in a group of patients undergoing pelvic radiotherapy using an 8 MV Elekta SL20 linear accelerator. Markers were placed on the skin entry and exit sites of the treatment beam and EPIs in both lateral and anterior pelvic views were acquired. Three observers independently assessed visibility success and failure using a subjective scoring system. Markers less than 5 mm in length or 0.9 mm in diameter were poorly visualized (<70% visualization success in lateral EPIs). The marker measuring 0.9 mm x 5 mm appears to be clinically optimal in pelvic radiotherapy patients (80% visualization success in lateral EPIs) and will be used for actual organ implantation.
Affiliation:
Academic Department of Radiation Oncology, University of Manchester, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK.
Citation:
An assessment of clinically optimal gold marker length and diameter for pelvic radiotherapy verification using an amorphous silicon flat panel electronic portal imaging device. 2005, 78 (932):737-41 Br J Radiol
Journal:
The British Journal of Radiology
Issue Date:
Aug-2005
URI:
http://hdl.handle.net/10541/76474
DOI:
10.1259/bjr/97956788
PubMed ID:
16046426
Type:
Article
Language:
en
ISSN:
0007-1285
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorHenry, Ann M-
dc.contributor.authorStratford, Julia-
dc.contributor.authorDavies, Julie-
dc.contributor.authorMcCarthy, Claire-
dc.contributor.authorSwindell, Ric-
dc.contributor.authorSykes, Jonathan R-
dc.contributor.authorMoore, Christopher J-
dc.contributor.authorPrice, Patricia M-
dc.contributor.authorKhoo, Vincent S-
dc.date.accessioned2009-08-06T10:09:31Z-
dc.date.available2009-08-06T10:09:31Z-
dc.date.issued2005-08-
dc.identifier.citationAn assessment of clinically optimal gold marker length and diameter for pelvic radiotherapy verification using an amorphous silicon flat panel electronic portal imaging device. 2005, 78 (932):737-41 Br J Radiolen
dc.identifier.issn0007-1285-
dc.identifier.pmid16046426-
dc.identifier.doi10.1259/bjr/97956788-
dc.identifier.urihttp://hdl.handle.net/10541/76474-
dc.description.abstractVerification of target organ position is essential for the accurate delivery of conformal radiotherapy. Megavoltage electronic portal imaging with flat panel amorphous silicon detectors delivers high quality images that can be used for verification of bony landmark position. Gold markers implanted into the target organ can be visualized and used as a surrogate of actual organ position. On-line compensation for marker displacement, by adjusting patient position, can reduce geometric errors associated with radiation delivery. This study assesses the optimal marker length and diameter to be used with an amorphous silicon (a-Si) flat panel detector and electronic portal images (EPIs), prior to implementation of a clinical programme of gold marker insertion in prostate cancer patients. Seven marker sizes varying from 3 mm to 8 mm in length and 0.8 mm to 1.1 mm in diameter were investigated in a group of patients undergoing pelvic radiotherapy using an 8 MV Elekta SL20 linear accelerator. Markers were placed on the skin entry and exit sites of the treatment beam and EPIs in both lateral and anterior pelvic views were acquired. Three observers independently assessed visibility success and failure using a subjective scoring system. Markers less than 5 mm in length or 0.9 mm in diameter were poorly visualized (<70% visualization success in lateral EPIs). The marker measuring 0.9 mm x 5 mm appears to be clinically optimal in pelvic radiotherapy patients (80% visualization success in lateral EPIs) and will be used for actual organ implantation.en
dc.language.isoenen
dc.subjectPelvic Canceren
dc.subject.meshElectronics, Medical-
dc.subject.meshGold-
dc.subject.meshHumans-
dc.subject.meshMovement-
dc.subject.meshObserver Variation-
dc.subject.meshPelvic Neoplasms-
dc.subject.meshPelvis-
dc.subject.meshRadiometry-
dc.subject.meshRadiotherapy Dosage-
dc.subject.meshRadiotherapy, Conformal-
dc.subject.meshSilicon-
dc.titleAn assessment of clinically optimal gold marker length and diameter for pelvic radiotherapy verification using an amorphous silicon flat panel electronic portal imaging device.en
dc.typeArticleen
dc.contributor.departmentAcademic Department of Radiation Oncology, University of Manchester, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK.en
dc.identifier.journalThe British Journal of Radiologyen
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