An inter-centre quality assurance network for IMRT verification: results of the ESTRO QUASIMODO project.

2.50
Hdl Handle:
http://hdl.handle.net/10541/76330
Title:
An inter-centre quality assurance network for IMRT verification: results of the ESTRO QUASIMODO project.
Authors:
Gillis, Sofie; De Wagter, Carlos; Bohsung, J; Perrin, Bruce A; Williams, Peter C; Mijnheer, Ben J
Abstract:
BACKGROUND AND PURPOSE: IMRT necessitates extension of existing inter-centre quality assurance programs due to its increased complexity. We assessed the feasibility of an inter-centre verification method for different IMRT techniques. MATERIALS AND METHODS: Eight European radiotherapy institutions of the QUASIMODO network, have designed an IMRT plan for a horseshoe-shaped PTV surrounding a cylindrical OAR in a simplified pelvic phantom. All centres applied common plan objectives but used their own equipment for planning and delivery. They verified the delivery of this plan according to a common protocol with radiographic film and ionisation chamber measurements. The irradiated films, the results of the ionisation chamber measurements and the computed dose distributions were sent to one analysis centre that compared the measured and computed dose distributions with the gamma method and composite dose-area histograms. RESULTS: 4% (relative to the prescribed dose) and 3mm (distance-to-agreement) were decided feasible gamma criteria. The composite dose-area histograms showed a maximum local deviation of 3.5% in the mean dose of the PTV and 5% in the OAR. Systematic differences could be identified, and in some cases explained. CONCLUSIONS: This multi-centre dosimetric verification study demonstrated both the feasibility of a multi-centre quality assurance network to evaluate any IMRT planning and delivery system combination, as well as the validity of the methodology involved.
Affiliation:
Department of Radiotherapy, Ghent University Hospital, Gent, Belgium. sifie.gillis@skynet.be
Citation:
An inter-centre quality assurance network for IMRT verification: results of the ESTRO QUASIMODO project. 2005, 76 (3):340-53 Radiother Oncol
Journal:
Radiotherapy and Oncology
Issue Date:
Sep-2005
URI:
http://hdl.handle.net/10541/76330
DOI:
10.1016/j.radonc.2005.06.021
PubMed ID:
16099521
Type:
Article
Language:
en
ISSN:
0167-8140
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorGillis, Sofie-
dc.contributor.authorDe Wagter, Carlos-
dc.contributor.authorBohsung, J-
dc.contributor.authorPerrin, Bruce A-
dc.contributor.authorWilliams, Peter C-
dc.contributor.authorMijnheer, Ben J-
dc.date.accessioned2009-08-05T12:04:26Z-
dc.date.available2009-08-05T12:04:26Z-
dc.date.issued2005-09-
dc.identifier.citationAn inter-centre quality assurance network for IMRT verification: results of the ESTRO QUASIMODO project. 2005, 76 (3):340-53 Radiother Oncolen
dc.identifier.issn0167-8140-
dc.identifier.pmid16099521-
dc.identifier.doi10.1016/j.radonc.2005.06.021-
dc.identifier.urihttp://hdl.handle.net/10541/76330-
dc.description.abstractBACKGROUND AND PURPOSE: IMRT necessitates extension of existing inter-centre quality assurance programs due to its increased complexity. We assessed the feasibility of an inter-centre verification method for different IMRT techniques. MATERIALS AND METHODS: Eight European radiotherapy institutions of the QUASIMODO network, have designed an IMRT plan for a horseshoe-shaped PTV surrounding a cylindrical OAR in a simplified pelvic phantom. All centres applied common plan objectives but used their own equipment for planning and delivery. They verified the delivery of this plan according to a common protocol with radiographic film and ionisation chamber measurements. The irradiated films, the results of the ionisation chamber measurements and the computed dose distributions were sent to one analysis centre that compared the measured and computed dose distributions with the gamma method and composite dose-area histograms. RESULTS: 4% (relative to the prescribed dose) and 3mm (distance-to-agreement) were decided feasible gamma criteria. The composite dose-area histograms showed a maximum local deviation of 3.5% in the mean dose of the PTV and 5% in the OAR. Systematic differences could be identified, and in some cases explained. CONCLUSIONS: This multi-centre dosimetric verification study demonstrated both the feasibility of a multi-centre quality assurance network to evaluate any IMRT planning and delivery system combination, as well as the validity of the methodology involved.en
dc.language.isoenen
dc.subjectCanceren
dc.subject.meshCommunity Networks-
dc.subject.meshDose Fractionation-
dc.subject.meshHumans-
dc.subject.meshModels, Theoretical-
dc.subject.meshNeoplasms-
dc.subject.meshQuality Assurance, Health Care-
dc.subject.meshRadiometry-
dc.subject.meshRadiotherapy-
dc.subject.meshReproducibility of Results-
dc.subject.meshUser-Computer Interface-
dc.titleAn inter-centre quality assurance network for IMRT verification: results of the ESTRO QUASIMODO project.en
dc.typeArticleen
dc.contributor.departmentDepartment of Radiotherapy, Ghent University Hospital, Gent, Belgium. sifie.gillis@skynet.been
dc.identifier.journalRadiotherapy and Oncologyen

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