The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.

2.50
Hdl Handle:
http://hdl.handle.net/10541/74932
Title:
The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.
Authors:
Leach, Martin O; Brindle, K; Evelhoch, J; Griffiths, John R; Horsman, Michael R; Jackson, A; Jayson, Gordon C ( 0000-0002-8515-8944 ) ; Judson, Ian R; Knopp, M; Maxwell, Ross J; McIntyre, D; Padhani, A; Price, P; Rathbone, R; Rustin, G; Tofts, P; Tozer, G; Vennart, W; Waterton, John C; Williams, S; Workman, Paul
Abstract:
Vascular and angiogenic processes provide an important target for novel cancer therapeutics. Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to noninvasively monitor the action of these therapeutics in early-stage clinical trials. This publication reports the outcome of a workshop that considered the methodology and design of magnetic resonance studies, recommending how this new tool might best be used.
Affiliation:
Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Royal Marsden Hospital, Sutton, Surrey, UK. martin.leach@icr.ac.uk
Citation:
The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations. 2005, 92 (9):1599-610 Br. J. Cancer
Journal:
British Journal of Cancer
Issue Date:
9-May-2005
URI:
http://hdl.handle.net/10541/74932
DOI:
10.1038/sj.bjc.6602550
PubMed ID:
15870830
Type:
Article
Language:
en
ISSN:
0007-0920
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorLeach, Martin O-
dc.contributor.authorBrindle, K-
dc.contributor.authorEvelhoch, J-
dc.contributor.authorGriffiths, John R-
dc.contributor.authorHorsman, Michael R-
dc.contributor.authorJackson, A-
dc.contributor.authorJayson, Gordon C-
dc.contributor.authorJudson, Ian R-
dc.contributor.authorKnopp, M-
dc.contributor.authorMaxwell, Ross J-
dc.contributor.authorMcIntyre, D-
dc.contributor.authorPadhani, A-
dc.contributor.authorPrice, P-
dc.contributor.authorRathbone, R-
dc.contributor.authorRustin, G-
dc.contributor.authorTofts, P-
dc.contributor.authorTozer, G-
dc.contributor.authorVennart, W-
dc.contributor.authorWaterton, John C-
dc.contributor.authorWilliams, S-
dc.contributor.authorWorkman, Paul-
dc.date.accessioned2009-07-22T10:46:22Z-
dc.date.available2009-07-22T10:46:22Z-
dc.date.issued2005-05-09-
dc.identifier.citationThe assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations. 2005, 92 (9):1599-610 Br. J. Canceren
dc.identifier.issn0007-0920-
dc.identifier.pmid15870830-
dc.identifier.doi10.1038/sj.bjc.6602550-
dc.identifier.urihttp://hdl.handle.net/10541/74932-
dc.description.abstractVascular and angiogenic processes provide an important target for novel cancer therapeutics. Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to noninvasively monitor the action of these therapeutics in early-stage clinical trials. This publication reports the outcome of a workshop that considered the methodology and design of magnetic resonance studies, recommending how this new tool might best be used.en
dc.language.isoenen
dc.subjectCanceren
dc.subject.meshAngiogenesis Inhibitors-
dc.subject.meshAntineoplastic Agents-
dc.subject.meshClinical Trials as Topic-
dc.subject.meshEvaluation Studies as Topic-
dc.subject.meshMagnetic Resonance Imaging-
dc.subject.meshNeoplasms-
dc.subject.meshReproducibility of Results-
dc.subject.meshTerminology as Topic-
dc.titleThe assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.en
dc.typeArticleen
dc.contributor.departmentCancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Royal Marsden Hospital, Sutton, Surrey, UK. martin.leach@icr.ac.uken
dc.identifier.journalBritish Journal of Canceren

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