2.50
Hdl Handle:
http://hdl.handle.net/10541/74923
Title:
Detection of recurrence in childhood solid tumors.
Authors:
Howell, Lisa; Mensah, Adjoa; Brennan, Bernadette M; Makin, Guy W J
Abstract:
BACKGROUND: Frequent follow-up and regular investigation are routine in pediatric oncology. However, there is little evidence regarding their value in the detection of recurrent disease. METHODS: The authors carried out a retrospective study of the follow-up of 186 children with solid tumors who were diagnosed between 1992 and 1996. The numbers of clinic visits, follow-up investigations, and (if appropriate) the mode of recurrence detection were recorded. RESULTS: The mean follow-up was 5.9 years. During this time, 37 recurrences were detected, symptomatically in 54% of patients, by routine investigation in 30% of patients, and at routine clinic appointment in 16% of patients. It was calculated that routine magnetic resonance imaging detected 1 recurrence for every 42 scans performed, routine computed tomography detected 1 recurrence for every 129 scans performed, and routine chest radiography detected 1 recurrence for every 257 films. CONCLUSIONS: The current results raise questions regarding the usefulness of such follow-up in children with solid tumors.
Affiliation:
Department of Pediatric Oncology, Royal Manchester Children's Hospital, Pendlebury, Manchester, United Kingdom.
Citation:
Detection of recurrence in childhood solid tumors. 2005, 103 (6):1274-9 Cancer
Journal:
Cancer
Issue Date:
15-Mar-2005
URI:
http://hdl.handle.net/10541/74923
DOI:
10.1002/cncr.20896
PubMed ID:
15674854
Type:
Article
Language:
en
ISSN:
0008-543X
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorHowell, Lisa-
dc.contributor.authorMensah, Adjoa-
dc.contributor.authorBrennan, Bernadette M-
dc.contributor.authorMakin, Guy W J-
dc.date.accessioned2009-07-22T10:31:18Z-
dc.date.available2009-07-22T10:31:18Z-
dc.date.issued2005-03-15-
dc.identifier.citationDetection of recurrence in childhood solid tumors. 2005, 103 (6):1274-9 Canceren
dc.identifier.issn0008-543X-
dc.identifier.pmid15674854-
dc.identifier.doi10.1002/cncr.20896-
dc.identifier.urihttp://hdl.handle.net/10541/74923-
dc.description.abstractBACKGROUND: Frequent follow-up and regular investigation are routine in pediatric oncology. However, there is little evidence regarding their value in the detection of recurrent disease. METHODS: The authors carried out a retrospective study of the follow-up of 186 children with solid tumors who were diagnosed between 1992 and 1996. The numbers of clinic visits, follow-up investigations, and (if appropriate) the mode of recurrence detection were recorded. RESULTS: The mean follow-up was 5.9 years. During this time, 37 recurrences were detected, symptomatically in 54% of patients, by routine investigation in 30% of patients, and at routine clinic appointment in 16% of patients. It was calculated that routine magnetic resonance imaging detected 1 recurrence for every 42 scans performed, routine computed tomography detected 1 recurrence for every 129 scans performed, and routine chest radiography detected 1 recurrence for every 257 films. CONCLUSIONS: The current results raise questions regarding the usefulness of such follow-up in children with solid tumors.en
dc.language.isoenen
dc.subjectCancer Invasivenessen
dc.subjectCancer Recurrenceen
dc.subjectCancer Stagingen
dc.subjectCanceren
dc.subject.meshAge Distribution-
dc.subject.meshChild-
dc.subject.meshChild, Preschool-
dc.subject.meshCohort Studies-
dc.subject.meshDisease-Free Survival-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshIncidence-
dc.subject.meshInfant-
dc.subject.meshMagnetic Resonance Imaging-
dc.subject.meshMale-
dc.subject.meshNeoplasm Invasiveness-
dc.subject.meshNeoplasm Recurrence, Local-
dc.subject.meshNeoplasm Staging-
dc.subject.meshNeoplasms-
dc.subject.meshRetrospective Studies-
dc.subject.meshRisk Assessment-
dc.subject.meshSex Distribution-
dc.subject.meshSurvival Analysis-
dc.subject.meshTomography, X-Ray Computed-
dc.titleDetection of recurrence in childhood solid tumors.en
dc.typeArticleen
dc.contributor.departmentDepartment of Pediatric Oncology, Royal Manchester Children's Hospital, Pendlebury, Manchester, United Kingdom.en
dc.identifier.journalCanceren

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.