Normal levels of serum IGF-I: determinants and validity of current reference ranges.

2.50
Hdl Handle:
http://hdl.handle.net/10541/71982
Title:
Normal levels of serum IGF-I: determinants and validity of current reference ranges.
Authors:
Brabant, Georg E; Wallaschofski, Henri
Abstract:
Insulin like growth factor I (IGF-I) represents the key marker for the evaluation of Growth hormone (GH) status. As a large number of determinants including age, gender, genetic factors, nutrition, and disease states influence IGF-I serum levels, accurate normative data are essential to translate patient data into diagnostic meaning or even use IGF-I levels for adequate monitoring of patients with an over- or under-active GH axis. Even though reference ranges have been developed in large cohorts of healthy subjects, the dependency of these data on a given assay technology argues for assay specific normative data for IGF-I.
Affiliation:
Department of Endocrinology, Christie Hospital, Wilmslow Rd, Manchester M20 4BX, UK. georg.Brabant@Manchester.ac.uk
Citation:
Normal levels of serum IGF-I: determinants and validity of current reference ranges. 2007, 10 (2):129-33 Pituitary
Journal:
Pituitary
Issue Date:
2007
URI:
http://hdl.handle.net/10541/71982
DOI:
10.1007/s11102-007-0035-9
PubMed ID:
17487588
Type:
Article
Language:
en
ISSN:
1386-341X
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorBrabant, Georg E-
dc.contributor.authorWallaschofski, Henri-
dc.date.accessioned2009-06-30T14:33:32Z-
dc.date.available2009-06-30T14:33:32Z-
dc.date.issued2007-
dc.identifier.citationNormal levels of serum IGF-I: determinants and validity of current reference ranges. 2007, 10 (2):129-33 Pituitaryen
dc.identifier.issn1386-341X-
dc.identifier.pmid17487588-
dc.identifier.doi10.1007/s11102-007-0035-9-
dc.identifier.urihttp://hdl.handle.net/10541/71982-
dc.description.abstractInsulin like growth factor I (IGF-I) represents the key marker for the evaluation of Growth hormone (GH) status. As a large number of determinants including age, gender, genetic factors, nutrition, and disease states influence IGF-I serum levels, accurate normative data are essential to translate patient data into diagnostic meaning or even use IGF-I levels for adequate monitoring of patients with an over- or under-active GH axis. Even though reference ranges have been developed in large cohorts of healthy subjects, the dependency of these data on a given assay technology argues for assay specific normative data for IGF-I.en
dc.language.isoenen
dc.subject.meshDisease Susceptibility-
dc.subject.meshFemale-
dc.subject.meshHuman Growth Hormone-
dc.subject.meshHumans-
dc.subject.meshInsulin-Like Growth Factor I-
dc.subject.meshMale-
dc.subject.meshReference Values-
dc.subject.meshReproducibility of Results-
dc.titleNormal levels of serum IGF-I: determinants and validity of current reference ranges.en
dc.typeArticleen
dc.contributor.departmentDepartment of Endocrinology, Christie Hospital, Wilmslow Rd, Manchester M20 4BX, UK. georg.Brabant@Manchester.ac.uken
dc.identifier.journalPituitaryen

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