2.50
Hdl Handle:
http://hdl.handle.net/10541/71961
Title:
Magnetic resonance imaging of primary vaginal carcinoma.
Authors:
Taylor, Malcolm B; Dugar, N; Davidson, Susan E; Carrington, Bernadette M
Abstract:
AIMS: To describe the magnetic resonance imaging (MRI) features of vaginal carcinoma and to suggest a role for MRI in its management. MATERIALS AND METHODS: Twenty-five patients with primary vaginal carcinoma treated at our institution between 1996 and 2005 were included in the study. The MRI examinations were reviewed and tumour dimensions, signal characteristics and involvement of pelvic structures were documented, as were sites of enlarged lymph nodes and metastases. Details of patient treatment and outcome were obtained from the clinical notes. RESULTS: The median patient age was 54 years (range 31-86 years). Tumour maximum diameter ranged from 1.6-11.3 cm (mean 3.7 cm). Most tumours were of iso-intense signal to muscle on T1-weighted images and hyper-intense to muscle on T2-weighted images. Eighty-eight percent of patients had tumour extending beyond the vagina and 56% of patients had Figo stage III or above tumours. Sixteen patients were treated with radiotherapy (two with chemoradiotherapy), five with surgery and four with supportive care. Ten patients (40%) died of their disease during the study period. The MRI stage of the tumour correlated with survival. CONCLUSION: MRI identified over 95% of primary vaginal tumours in the present study, enabled radiological staging, which correlated with outcome, and provided information of use in treatment planning.
Affiliation:
Department of Diagnostic Radiology, Christie Hospital NHS Trust, Withington, Manchester, UK. ben.taylor@christie-tr.nwest.nhs.uk
Citation:
Magnetic resonance imaging of primary vaginal carcinoma. 2007, 62 (6):549-55 Clin Radiol
Journal:
Clinical Radiology
Issue Date:
Jun-2007
URI:
http://hdl.handle.net/10541/71961
DOI:
10.1016/j.crad.2007.01.008
PubMed ID:
17467392
Type:
Article
Language:
en
ISSN:
0009-9260
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorTaylor, Malcolm B-
dc.contributor.authorDugar, N-
dc.contributor.authorDavidson, Susan E-
dc.contributor.authorCarrington, Bernadette M-
dc.date.accessioned2009-06-30T14:18:35Z-
dc.date.available2009-06-30T14:18:35Z-
dc.date.issued2007-06-
dc.identifier.citationMagnetic resonance imaging of primary vaginal carcinoma. 2007, 62 (6):549-55 Clin Radiolen
dc.identifier.issn0009-9260-
dc.identifier.pmid17467392-
dc.identifier.doi10.1016/j.crad.2007.01.008-
dc.identifier.urihttp://hdl.handle.net/10541/71961-
dc.description.abstractAIMS: To describe the magnetic resonance imaging (MRI) features of vaginal carcinoma and to suggest a role for MRI in its management. MATERIALS AND METHODS: Twenty-five patients with primary vaginal carcinoma treated at our institution between 1996 and 2005 were included in the study. The MRI examinations were reviewed and tumour dimensions, signal characteristics and involvement of pelvic structures were documented, as were sites of enlarged lymph nodes and metastases. Details of patient treatment and outcome were obtained from the clinical notes. RESULTS: The median patient age was 54 years (range 31-86 years). Tumour maximum diameter ranged from 1.6-11.3 cm (mean 3.7 cm). Most tumours were of iso-intense signal to muscle on T1-weighted images and hyper-intense to muscle on T2-weighted images. Eighty-eight percent of patients had tumour extending beyond the vagina and 56% of patients had Figo stage III or above tumours. Sixteen patients were treated with radiotherapy (two with chemoradiotherapy), five with surgery and four with supportive care. Ten patients (40%) died of their disease during the study period. The MRI stage of the tumour correlated with survival. CONCLUSION: MRI identified over 95% of primary vaginal tumours in the present study, enabled radiological staging, which correlated with outcome, and provided information of use in treatment planning.en
dc.language.isoenen
dc.subjectVaginal Canceren
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshCombined Modality Therapy-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMagnetic Resonance Imaging-
dc.subject.meshMiddle Aged-
dc.subject.meshNeoplasm Invasiveness-
dc.subject.meshTreatment Outcome-
dc.subject.meshVagina-
dc.subject.meshVaginal Neoplasms-
dc.titleMagnetic resonance imaging of primary vaginal carcinoma.en
dc.typeArticleen
dc.contributor.departmentDepartment of Diagnostic Radiology, Christie Hospital NHS Trust, Withington, Manchester, UK. ben.taylor@christie-tr.nwest.nhs.uken
dc.identifier.journalClinical Radiologyen
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